Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.
[No authors listed]
摘要
Prematurity is a risk factor for severe respiratory syncytial virus bronchiolitis. We show that genetic factors in innate immune genes (IFNA13, IFNAR2, IL27, NFKBIA, C3, IL1RN, TLR5), in innate and adaptive immunity (IFNG), and in airway remodeling genes (ADAM33 and TGFBR1), affect disease susceptibility to a different extent in preterm children, born with underdeveloped lungs, than in term children.
KEYWORDS: {{ getKeywords(articleDetailText.words) }}
基因功能
- {{$index+1}}.{{ gene }}
基因
C3, Tlr5, Adam33, Il1rn, TLR6, CCL26, IRF9, CXCL13, GNLY, CYSLTR1, CCL27, CHUK, CCR3, CCR5, CSF2, CSF3, CSF3R, IL23R, CTLA4, ADRB2, EDN1, FCER1A, MS4A2, FCER2, FOS, IL17RA, ALOX5, IL27, GATA3, HAVCR1, CHIA, CXCR3, NR3C1, CXCL1, CXCL2, CXCL3, IL19, TBX21, GZMA, GZMB, HDC, CD209, HNMT, ICAM1, IFNA1, IFNA2, IFNA5, IFNA6, IFNA8, IFNA13, IFNA14, IFNAR1, IFNAR2, IFNG, IFNGR2, IKBKB, IL1A, IL1B, IL1R1, IL1RN, IL2, IL2RA, IL2RB, IL2RG, IL3, IL4, IL4R, IL5, IL5RA, IL6, IL6R, IL7, CXCL8, IL9, CXCR2, IL9R, IL10, IL10RA, IL10RB, IL11, IL12A, IL12B, IL12RB1, IL12RB2, IL13, IL13RA1, IL13RA2, IL15, IL15RA, IL16, IL17A, IL18, IRF1, IRF3, IRF5, ITGB2, JAK1, JAK2, JUN, ARG1, NPSR1, LTA, LTF, MBL2, CXCL9, MUC1, MUC2, MUC4, MUC5AC, MUC7, NCF2, NFKB2, NFKBIA, NGF, NGFR, NOS1, NOS2, IL20, IL22, FOXP3, PHF11, IRAK4, TLR7, TLR8, PECAM1, PF4, TLR9, PPBP, PRF1, IL26, CCL28, PSMB8, PTGS2, DPP10, CXCL16, IL21, CCL1, CCL2, CCL4, CCL5, CCL7, CCL8, CCL11, CCL13, CCL14, CCL15, CCL16, CCL17, CCL18, CCL19, CCL22, CCL23, CCL24, CCL25, CXCL6, CXCL5, SELL, NOD2, SFTPB, SFTPC, SFTPD, STAT1, STAT3, STAT4, STAT5A, STAT6, TAC1, TACR2, TACR3, TAP1, TAP2, TGFB1, TGFB2, TGFBR1, TLR1, TLR2, TLR3, TLR4, TLR5, TNF, TNFRSF1A, TNFRSF1B, C3, C5, MUC5B, CCR2, TYK2, SCGB1A1, VCAM1, VDR, VIP, IL1R2, ADAM33, TLR10, CASP1, HAVCR2, IKBKAP, IL18R1, SOCS2, SOCS3, CD14, CD28, CD80, CD86, IL27RA, CXCL14, CD40, CD40LG, CDH1
原始数据
| Sample name | Organism | Experiment title | Sample type | Library instrument | Attributes | |||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| {{attr}} | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| {{ dataList.sampleTitle }} | {{ dataList.organism }} | {{ dataList.expermentTitle }} | {{ dataList.sampleType }} | {{ dataList.libraryInstrument }} | {{ showAttributeName(index,attr,dataList.attributes) }} | |||||||||||||||||||||||||||||||||||||||||||||||||
文献解读
| {{ list.authorName }} {{ list.authorName }} |
