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3595 IL12RB2

3595

IL12RB2

interleukin 12 receptor subunit beta 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition interleukin 12 receptor subunit beta 2

研究结论

Date Results Publications
2020-03-14 12:11:00 Mutation analysis showed three previously reported mutations, two novel mutations in IL-12 R (beta1/beta2), and one previously reported mutation in IL-12 Mendelian Susceptibility to Mycobacterial Disease patients. 31158284
2019-10-05 12:38:00 we analyzed common variants located in genes of the and signaling pathways in patients with myasthenia gravis. 29576322
2018-11-03 10:11:00 The Cox proportional hazard models revealed that IL12Rb2 and p38MAPK predicted a long OS. To the best of our knowledge, the present study is the first to reveal a close association between IL12Rb2 and p38MAPK, and their possible function in nonsmall cell lung cancer progression 29956791
2018-07-14 10:28:00 Tumor cell differentiation is associated with TILs' expression of IL-12Rbeta2, and an IL-12Rbeta2(+) TIL ratio >/=35%) indicates favorable prognosis in LC 29103744
2017-10-28 10:57:00 inhibition of the H3K27 demethylase JMJD3 in naive CD4 T cells demonstrates how critically important molecules required for T cell differentiation, such as JAK2 and IL12RB2, are regulated by H3K27me3. 28947543

名称对应

Type IDs
Gene
UniProtKB-ID: I12R2_HUMAN, B7ZB60_HUMAN, A0A0A0MTN7_HUMAN, B4DGA4_HUMAN
UniprotKB: Q99665, B7ZB60, A0A0A0MTN7, B4DGA4
UniParc: UPI001632384B, UPI00019153AE, UPI000206516C, UPI0000046B13, UPI00003BF72D, UPI00017A6EE8
EMBL: AK294494, CH471059, AK316525, BC104772, AL358512, AL389925, U64198, AY640177, BC143249, BC104774
Ensembl: ENSG00000081985
KO: hsa:3595
Nucleutide sequences
EMBL-CDS: EAX06499.1, AAI43250.1, AAB36675.1, AAI04775.1, AAT45456.1, AAI04773.1, BAH14896.1, BAG57715.1
Ensembl_TRS: ENST00000544434, ENST00000648487, ENST00000371000, ENST00000674203, ENST00000262345, ENST00000541374
Protein sequencees
Ensembl_PRO: ENSP00000497959, ENSP00000501329, ENSP00000442443, ENSP00000360039, ENSP00000262345, ENSP00000445276
RefSeq: NP_001361188.1, XP_011539685.1, XP_016856693.1, NP_001245144.1, XP_005270885.1, NP_001550.1, NP_001245143.1, NP_001245145.1, XP_005270884.1, XP_011539686.1, XP_016856692.1, NP_001306162.1, XP_006710680.1
Others
UniRef100: UniRef100_B7ZB60, UniRef100_A0A0A0MTN7, UniRef100_Q99665, UniRef100_B4DGA4
UniRef90: UniRef90_A0A2K5VNI1, UniRef90_Q99665-2, UniRef90_Q99665
UniRef50: UniRef50_Q99665, UniRef50_A0A5G2QWD9
UniGene: Hs.479347
CCDS: CCDS58006.1, CCDS58007.1, CCDS638.1

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