| Type | Description |
|---|---|
| Definition | surfactant protein C |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 12:01:00 | Mutations in the surfactant protein C gene were an important cause of childhood interstitial lung disease in Chinese population. | 31462320 |
| 2020-01-04 11:29:00 | miR-629-3p-meditated downregulation of SFTPC may promote lung adenocarcinoma progression | 31379200 |
| 2019-10-26 11:05:00 | NKX2-1 mutations result in decreased expression of SFTPB and SFTPC | 29538355 |
| 2019-09-14 12:24:00 | Heterozygous previously described rare or novel variants in surfactant proteins genes ABCA3, SFTPB and SFTPC were identified in 24 newborn infants with particularly severe respiratory distress syndrome. Interaction of developmental immaturity of surfactant production in association with abnormalities of surfactant metabolism of genetic origin may have a synergic worsening phenotypic effect. | 29255193 |
| 2019-08-03 12:31:00 | For the first time, this study could show that infantile labial glands show expression of the surfactant proteins (SP) SP-A, SP-B, SP-C, and SP-D in acinar cells and the duct system in different intensities. | 29601229 |
| Type | IDs |
|---|---|
| Synonymous | BRICD6, PSP-C, SFTP2, SMDP2, SP-C |
| Gene |
UniProtKB-ID:
PSPC_HUMAN,
A0A0A0MTC9_HUMAN,
A0A0S2Z4Q0_HUMAN,
E5RI64_HUMAN
UniprotKB:
P11686,
A0A0A0MTC9,
A0A0S2Z4Q0,
E5RI64
UniParc:
UPI0000E5AE47,
UPI000020FCC5,
UPI000002B1C6,
UPI00001327FC,
UPI0000140371
EMBL:
AY357924,
J03553,
J03890,
U02948,
DQ884411,
AY337315,
KU178330,
AK315742,
KU178329,
CH471080,
AC105206,
J03517,
BC005913
Ensembl:
ENSG00000168484
KO:
hsa:6440
|
| Nucleutide sequences |
EMBL-CDS:
AAA36631.1,
AAQ67734.1,
EAW63707.1,
AAP88034.1,
AAA36634.1,
AAC32023.1,
ABI63378.1,
AAC32022.1,
BAG38097.1,
AAH05913.1,
AAB60332.1,
ALQ33788.1,
ALQ33787.1
Ensembl_TRS:
ENST00000318561,
ENST00000521315,
ENST00000524255
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000316152,
ENSP00000430410,
ENSP00000429552
RefSeq:
NP_001372588.1,
NP_001372583.1,
NP_001372587.1,
NP_003009.2,
NP_001372586.1,
NP_001304708.1,
NP_001304709.1,
NP_001304707.1,
NP_001165828.1,
XP_011542915.1,
NP_001372589.1,
NP_001165881.1,
NP_001372584.1,
NP_001372582.1,
NP_001372585.1
|
| Others |
UniRef100:
UniRef100_E5RI64,
UniRef100_P11686,
UniRef100_A0A0S2Z4Q0,
UniRef100_A0A0A0MTC9
UniRef90:
UniRef90_E5RI64,
UniRef90_P11686
UniRef50:
UniRef50_P22398,
UniRef50_P11686
UniGene:
Hs.1074
CCDS:
CCDS55209.1,
CCDS43722.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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