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56477 CCL28

56477

CCL28

C-C motif chemokine ligand 28

protein-coding

Homo sapiens

基因描述

Type Description
Definition C-C motif chemokine ligand 28

研究结论

Date Results Publications
2021-03-06 13:31:00 Hypoxia Induces Overexpression of CCL28 to Recruit Treg Cells to Enhance Angiogenesis in Lung Adenocarcinoma. 33639074
2018-05-12 12:04:00 this review discusses the role of CCL28 in innate and adaptive immunity 28843907
2018-04-28 10:48:00 Results show that CCL28 expression was up-regulated under hypoxic condition in lung adenocarcinoma cells. Besides other effects on tumor biology such as immunosuppression, CCL28 could promote angiogenesis in lung adenocarcinoma by directly activating its receptor, CCR3, on microvascular endothelial cells. 27250766
2018-04-21 10:19:00 our results show for the first time that CCL28 contributes to breast cancer progression through the ERK/MAPKmediated anti-apoptotic and metastatic signaling pathway. Antagonists of CCL28 and the MAPK signaling pathway may be used synergistically to treat breast cancer patients. 28713975
2018-03-03 10:10:00 HCC recruits Tregs to promote angiogenesis under hypoxic condition by upregulating CCL28 expression. These findings establish a link between Tregs and hypoxia in HCC growth and may provide a new potential therapeutic target for treating HCC. 27716621

名称对应

Type IDs
Synonymous CCK1, MEC, SCYA28
Gene
UniProtKB-ID: CCL28_HUMAN, A0N0Q3_HUMAN, D6RC73_HUMAN
UniprotKB: Q9NRJ3, A0N0Q3, D6RC73
UniParc: UPI000020CA61, UPI00001362E3, UPI0001D9A876
EMBL: BC062668, EF064761, CH471119, AC025457, AF266504, AF220210, BC069532, AK312120, HM067700, AF110384
Ensembl: ENSG00000151882
KO: hsa:56477
Nucleutide sequences
EMBL-CDS: AAG43193.1, AAH69532.1, AAF87205.1, AAH62668.1, ADH95184.1, AAG16691.1, ABK41944.1, EAW56058.1, EAW56057.1, BAG35056.1, EAW56059.1
Gene_ORFName: hCG_36937, hCG_36937
Ensembl_TRS: ENST00000489442, ENST00000361115, ENST00000513525
Protein sequencees
Ensembl_PRO: ENSP00000354416, ENSP00000426424, ENSP00000422369
RefSeq: NP_001288802.1, NP_001288804.1, NP_001288803.1, NP_683513.1
Others
UniRef100: UniRef100_Q9NRJ3
UniRef90: UniRef90_Q9NRJ3
UniRef50: UniRef50_Q9NRJ3
UniGene: Hs.656904
CCDS: CCDS3944.1

全选

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