| Type | Description |
|---|---|
| Definition | interleukin 27 receptor subunit alpha |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:31:00 | Loss of IL-27Ralpha Results in Enhanced Tubulointerstitial Fibrosis Associated with Elevated Th17 Responses. | 32522836 |
| 2018-02-24 11:57:00 | this study found elevated expression of IL-27 in human peripheral serum and elevated expression of its specific receptor (wsx-1) on fetal membranes in cases of preterm birth | 28756371 |
| 2017-08-12 12:07:00 | These results identify IL-27 and its specific receptor IL27RA as a critical immune axis for the antiviral immune response and as robust correlates of viral load and proviral reservoir size in mononuclear leukocytes in HIV infection. | 28592538 |
| 2016-11-05 11:43:00 | Findings demonstrated that IL-27 and IL-27R were elevated in multiple sclerosis lesions and that local IL-27 can modulate immune properties of astrocytes and infiltrating immune cells | 26649511 |
| 2015-11-07 11:55:00 | The significant expression of IL-27 in TB and the negative influence of IL-27R on T cell function demonstrate the pathway by which this cytokine/receptor pair is detrimental in TB. | 26282876 |
| Type | IDs |
|---|---|
| Synonymous | CRL1, IL-27RA, IL27R, TCCR, WSX1, zcytor1 |
| Gene |
UniProtKB-ID:
I27RA_HUMAN
UniprotKB:
Q6UWB1
UniParc:
UPI0000039E1F
EMBL:
EF064719,
BC028003,
AF106912,
AY358876,
AF053004,
AF265242
Ensembl:
ENSG00000104998,
ENSG00000288185
KO:
hsa:9466
|
| Nucleutide sequences |
EMBL-CDS:
AAG27297.1,
AAQ89235.1,
AAH28003.1,
ABK41902.1,
AAG26090.1,
AAC39755.1
Gene_ORFName:
UNQ296/PRO336
Ensembl_TRS:
ENST00000263379,
ENST00000672064
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263379,
ENSP00000500946
RefSeq:
NP_004834.1
|
| Others |
UniRef100:
UniRef100_Q6UWB1
UniRef90:
UniRef90_Q6UWB1
UniRef50:
UniRef50_Q6UWB1
UniGene:
Hs.132781,
Hs.352155
CCDS:
CCDS12303.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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