| Type | Description |
|---|---|
| Definition | C-X-C motif chemokine ligand 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:25:00 | Gene expression and methylation profiles identified CXCL3 and CXCL8 as key genes for diagnosis and prognosis of colon adenocarcinoma. | 31709538 |
| 2021-03-13 13:14:00 | CXCL3 overexpression promotes the tumorigenic potential of uterine cervical cancer cells via the MAPK/ERK pathway. | 31667838 |
| 2020-02-29 11:32:00 | Study demonstrated that CXCL3 is not only considerably upregulated in colon cancer (CC) tumor tissue but also has potential diagnostic value in patients with CC. Survival analysis suggested that CXCL3 may serve as a potential prognostic biomarker in CC. | 31545503 |
| 2019-12-14 10:19:00 | hydrophobic pocket is in the vicinity of GAG binding region of CXCL3, a molecular determinant in leukocyte trafficking | 30528777 |
| 2019-04-13 12:32:00 | Migration, invasion, proliferation and tube-formation capability of HTR-8/SVneo trophoblast cells transfected with siRNA-CXCL3 were suppressed by down-regulation of CXCL3, while those behaviors of HTR-8/SVneo cells transfected with pEZ-CXCL3 were enhanced by upregulation of CXCL3. Nevertheless, the apoptosis of HTR-8/SVneo cells was not affected by either siRNA or overexpression plasmid. | 29884302 |
| Type | IDs |
|---|---|
| Synonymous | CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3 |
| Gene |
UniProtKB-ID:
CXCL3_HUMAN
UniprotKB:
P19876
UniParc:
UPI0000000DFD
EMBL:
AC097709,
BC065743,
CH471057,
M36821,
BC016308,
X53800
Ensembl:
ENSG00000163734
KO:
hsa:2921
|
| Nucleutide sequences |
EMBL-CDS:
AAH16308.1,
AAY41006.1,
AAH65743.1,
EAX05698.1,
CAA37809.1,
AAA63184.1
Ensembl_TRS:
ENST00000296026
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296026
RefSeq:
NP_002081.2
|
| Others |
UniRef100:
UniRef100_P19876
UniRef90:
UniRef90_P19876
UniRef50:
UniRef50_P09341
UniGene:
Hs.89690
CCDS:
CCDS34007.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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