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51135 IRAK4

51135

IRAK4

interleukin 1 receptor associated kinase 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition interleukin 1 receptor associated kinase 4

研究结论

Date Results Publications
2020-10-24 14:02:00 IRAK4 mediates colitis-induced tumorigenesis and chemoresistance in colorectal cancer. 31527315
2020-07-11 11:15:00 IRAK1 and IRAK4 signaling proteins are dispensable in the response of human neutrophils to Mycobacterium tuberculosis infection. 31702785
2020-01-04 11:26:00 Dimethyl fumarate blocks IRAK4-MyD88 interactions and IRAK4-mediated cytokine production in a cysteine 13-dependent manner. 30885957
2019-12-14 12:14:00 structures reveal conformational flexibility of unphosphorylated IRAK4 and provide unexpected insights into the potential use of small molecules to modulate IRAK4 activity in cancer, autoimmunity, and inflammation 30679311
2019-11-16 13:24:00 miR-544 may participate in controlling inflammation and apoptosis after ischemia-reperfusion by targeting IRAK4. 30229835

名称对应

Type IDs
Synonymous IPD1, IRAK-4, NY-REN-64, REN64
Gene
UniProtKB-ID: IRAK4_HUMAN, B4E359_HUMAN, Q69FE3_HUMAN, B2RAP9_HUMAN
UniprotKB: Q9NWZ3, B4E359, Q69FE3, B2RAP9
UniParc: UPI0000401AEB, UPI00017A8857, UPI0001750675, UPI000004ABE6
EMBL: AY186092, AK000528, AY340966, AF155118, AY340962, AY340964, AY340965, AK299944, BC013316, AK314288, AY730682, CH471111, KU178631, AC093012, AF445802, AK304583, AY340963, AY340967
Ensembl: ENSG00000198001
KO: hsa:51135
Nucleutide sequences
EMBL-CDS: BAA91232.1, AAN75440.1, AAR02361.1, AAD42884.1, AAR02360.1, BAG61774.1, AAM15772.1, AAR02362.1, AAH13316.1, AAR02363.1, BAG65371.1, ALQ34089.1, EAW57867.1, AAR02358.1, AAR02359.1, AAX22228.1, BAG36946.1
Gene_ORFName: hCG_39494
Ensembl_TRS: ENST00000431837, ENST00000613694, ENST00000440781, ENST00000551736
Protein sequencees
Ensembl_PRO: ENSP00000390327, ENSP00000446490, ENSP00000479889, ENSP00000408734
RefSeq: XP_005269000.1, XP_005269006.1, NP_057207.2, NP_001338273.1, XP_011536733.1, XP_006719505.1, NP_001138730.1, NP_001338271.1, NP_001107654.1, XP_006719503.1, XP_005269002.1, NP_001338274.1, XP_016874879.1, NP_001338269.1, NP_001338272.1, NP_001138728.1, XP_011536735.1, NP_001338268.1, XP_005269001.1, NP_001338267.1, NP_001138729.1, NP_001338270.1, XP_024304776.1, XP_006719501.1
Others
UniRef100: UniRef100_B2RAP9, UniRef100_Q9NWZ3, UniRef100_B4E359
UniRef90: UniRef90_B4E359, UniRef90_Q9NWZ3
UniRef50: UniRef50_B4E359, UniRef50_Q9NWZ3
UniGene: Hs.138499
CCDS: CCDS8744.1, CCDS44862.1

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