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27159 CHIA

27159

CHIA

chitinase acidic

protein-coding

Homo sapiens

基因描述

Type Description
Definition chitinase acidic

研究结论

Date Results Publications
2019-08-17 12:46:00 AMCase expression was significantly higher in helminths-infected patients than the noninfected, or protozoa infected. 30117166
2018-08-04 11:20:00 rs10494132 polymorphism of CHIA might be a risk factor for asthma. 29233108
2017-07-01 12:37:00 we showed that M at the position 61 is highly conserved in the many mammals other than orangutan and humans. In addition, introduction of M61R and M61I to WT mouse AMCase lead to a significant reduction of its chitinolytic activity. Taken together, our present and previous data by Seibold et al. (2009) indicate that G339T (R61M) in humans is associated with asthma protection in the fashion of gain of function 27702777
2017-07-01 11:33:00 This is the first report on the association between low-frequency and common variants in the chitinases-related genes CHIA and CHI3L1 with the intensity of specific IgE to ABA-1 in a population naturally exposed to Ascaris and with Bet v 1 in a Swedish population. 27977724
2015-01-17 11:46:00 These data provide the experimental evidence that telomere shortening and related inflammatory proteins are associated with human IgAN, and it could be a new direction for the disease progression study. 24903994

名称对应

Type IDs
Synonymous AMCASE, CHIT2, TSA1902
Gene
UniProtKB-ID: CHIA_HUMAN, Q2VT96_HUMAN, A8K3T7_HUMAN, Q1M0P3_HUMAN, Q1M0P4_HUMAN
UniprotKB: Q9BZP6, Q2VT96, A8K3T7, Q1M0P3, Q1M0P4
UniParc: UPI0000D6881C, UPI000004A10D, UPI00015DA72A, UPI0000D6881B, UPI00000727DC, UPI0000661E34, UPI00001DFF7A
EMBL: AL356387, AY789445, AB025008, BC047336, AY911311, AF290004, AY825504, AB025009, BC036339, AL513202, AK290702, BC106910, AY789444, AY911310
Ensembl: ENSG00000134216
KO: hsa:27159
Nucleutide sequences
EMBL-CDS: AAI06911.1, AAX81431.1, BAA86981.1, BAA86980.1, AAG60019.1, AAX81432.1, AAH36339.2, AAH47336.2, AAX54833.1, BAF83391.1, AAX81434.1, AAX81433.1
Ensembl_TRS: ENST00000430615, ENST00000343320, ENST00000353665, ENST00000451398, ENST00000369740, ENST00000483391
Protein sequencees
Ensembl_PRO: ENSP00000341828, ENSP00000338970, ENSP00000390476, ENSP00000436946, ENSP00000391132, ENSP00000358755
RefSeq: NP_001035713.1, XP_006710640.1, XP_016856537.1, NP_001244932.1, NP_001244930.1, NP_001244931.1, NP_001244933.1, NP_970615.2, NP_068569.2, NP_001244934.1, XP_016856536.1
Others
UniRef100: UniRef100_Q2VT96, UniRef100_A8K3T7, UniRef100_Q9BZP6, UniRef100_Q1M0P4, UniRef100_Q1M0P3
UniRef90: UniRef90_A8K3T7, UniRef90_Q1M0P4, UniRef90_Q1M0P3, UniRef90_Q9BZP6
UniRef50: UniRef50_Q9BZP6, UniRef50_H2N6E4, UniRef50_L5LXP1, UniRef50_G3QZM1
UniGene: Hs.128814
CCDS: CCDS58017.1, CCDS832.1, CCDS41368.1

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