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4688 NCF2

4688

NCF2

neutrophil cytosolic factor 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition neutrophil cytosolic factor 2

研究结论

Date Results Publications
2020-09-19 16:30:00 NCF2, MYO1F, S1PR4, and FCN1 as potential noninvasive diagnostic biomarkers in patients with obstructive coronary artery: A weighted gene co-expression network analysis. 31245869
2020-02-08 11:35:00 Studies indicate that the G allele of neutrophil cytosolic factor 2 (NCF2) rs10911362 provided a protective role against tuberculosis (TB) risk in the Western Chinese Han population. 31794672
2019-11-09 11:36:00 Activation of by membranolytic insults that result in high levels of intracellular calcium (higher than physiological neutrophil activation) leads to rapid citrullination of p47(phox)/NCF1 and p67(phox)/NCF2, as well as their dissociation from duanyu15634 30323221
2019-03-02 12:25:00 Results show that NCF2 expression is highly upregulated in gastric cancer (GC) tumors. However, its mRNA is targeted by miR-532 and its expression repressed. More importantly, NCF2 can in turn upregulate LINC01410 expression via NF-kappaB in GC. 29483646
2017-12-09 12:19:00 We analyzed the clinical and laboratory findings of CGD with mutations in the NCF2 gene from amongst our cohort of CGD patients. A homozygous mutation (c.835_836delAC, p.T279fsX294), a deletion in NCF2 gene was found in two cases. In the third case, two heterozygous mutations were detected, IVS13-2A>T on one allele and c.1099C>T (p.) on the other allele. 28035544

名称对应

Type IDs
Synonymous NCF-2, NOXA2, P67-PHOX, P67PHOX
Gene
UniProtKB-ID: NCF2_HUMAN, A0A0S2Z457_HUMAN
UniprotKB: P19878, A0A0S2Z457
UniParc: UPI0000E05F75, UPI0001AE7971, UPI0000000A07, UPI00017A74A0
EMBL: U00787, U00776, U00788, U00779, BT007439, AL137800, BC001606, AK296672, AK312666, AK298713, U00786, U00783, CH471067, AF527950, DQ314879, U00778, M32011, U00777, U00782, U00784, U00785, U00781, U00780, KU178216
Ensembl: ENSG00000116701
KO: hsa:4688
Nucleutide sequences
EMBL-CDS: AAH01606.1, BAG59269.1, EAW91160.1, AAB60320.1, BAG60869.1, AAA36379.1, AAM89263.1, BAG35548.1, ABC40738.1, AAP36107.1, ALQ33674.1
Ensembl_TRS: ENST00000413720, ENST00000418089, ENST00000367536, ENST00000367535
Protein sequencees
Ensembl_PRO: ENSP00000407217, ENSP00000399294, ENSP00000356505, ENSP00000356506
RefSeq: NP_001121123.1, NP_001177723.1, NP_000424.2, NP_001177718.1, XP_011507882.1, XP_011507883.1, XP_005245264.1
Others
UniRef100: UniRef100_P19878
UniRef90: UniRef90_P19878
UniRef50: UniRef50_P19878
UniGene: Hs.587558
CCDS: CCDS53447.1, CCDS1356.1, CCDS53446.1

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