| Type | Description |
|---|---|
| Definition | tachykinin precursor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:47:00 | Skin stimulation ex vivo with the neuropeptide substance P (SP), mimicking neurogenic skin inflammation, significantly increased the number of CD68+macrophages in the papillary dermis without altering intracutaneous macrophages proliferation or apoptosis. | 31971954 |
| 2019-12-28 12:28:00 | These findings establish a novel regulatory axis, LOC134466/hsa-miR-196a-5p/TAC1. Downregulation of the axis promoted EC development through TACR3, which further activated neuroactive ligand-receptor interaction. | 30485833 |
| 2019-07-13 12:58:00 | Increased serum SP levels and NK1R tissue distribution were observed in patients with breast cancer as compared with their controls. | 30684188 |
| 2019-06-22 10:42:00 | Based on the results shown here, CGRP can mitigate augmenting effects of SP on BMP2 signaling and the three pathways potentially converge on Runx2 to regulate BMP2-induced bone differentiation. | 29745819 |
| 2019-03-02 10:58:00 | The results of this study show a significant upregulation of TAC1 in the medial area frontopolaris which is a node in the limbic-cortical network and known to be susceptible for gray matter loss and behavioral dysfunction in patients with depression. | 29478144 |
| Type | IDs |
|---|---|
| Synonymous | Hs.2563, NK2, NKNA, NPK, TAC2 |
| Gene |
UniProtKB-ID:
TKN1_HUMAN,
Q9Y494_HUMAN
UniprotKB:
P20366,
Q9Y494
UniParc:
UPI000002B55C,
UPI000002B55D,
UPI0000072A11,
UPI000002C712,
UPI000002B55B
EMBL:
CH471091,
AF050658,
CH236949,
M68907,
AF050655,
CR541730,
AF050656,
CR407602,
M68906,
AF050657,
U37529,
BC018047,
AK222957,
X54469,
AC004140
Ensembl:
ENSG00000006128
KO:
hsa:6863
|
| Nucleutide sequences |
EMBL-CDS:
EAL24119.1,
AAQ96890.1,
EAW76736.1,
CAA38351.1,
AAH18047.1,
EAW76735.1,
CAG28529.1,
AAQ96891.1,
AAA60159.1,
BAD96677.1,
EAW76734.1,
AAA60160.1,
AAC15702.1,
AAC15704.1,
AAQ96888.1,
AAQ96889.1,
EAW76737.1,
AAA79195.1,
AAC15701.1,
EAL24117.1,
EAL24118.1,
EAL24116.1,
CAG46531.1,
AAC15703.1
Ensembl_TRS:
ENST00000346867,
ENST00000350485,
ENST00000319273
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000321106,
ENSP00000289574,
ENSP00000289576
RefSeq:
NP_054702.1,
NP_054704.1,
NP_054703.1,
NP_003173.1
|
| Others |
UniRef100:
UniRef100_A0A2J8WJK4,
UniRef100_P20366
UniRef90:
UniRef90_A0A2K6QRE8,
UniRef90_P20366
UniRef50:
UniRef50_P20366,
UniRef50_A0A2K6QRE8
UniGene:
Hs.2563
CCDS:
CCDS5649.1,
CCDS5650.1,
CCDS5651.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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