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5696 PSMB8

5696

PSMB8

proteasome subunit beta 8

protein-coding

Homo sapiens

基因描述

Type Description
Definition proteasome subunit beta 8

研究结论

Date Results Publications
2021-03-13 13:24:00 LMP7 inhibits the activation of NLRP3 inflammasome through interaction with NLRP3. 32782149
2020-10-31 13:19:00 The inducible beta5i proteasome subunit contributes to proinsulin degradation in GRP94-deficient beta-cells and is overexpressed in type 2 diabetes pancreatic islets. 32255680
2020-10-24 13:58:00 miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8. 31559672
2020-04-18 11:01:00 The dominant model of LMP2 CfoI might be a risk factor for IDDM in Asian population. Whereas, the allelic and dominant models of LMP7 G37360T might be protective factors for IDDM in Caucasian population 32221071
2019-07-20 13:01:00 co-inhibition of LMP2 and LMP7 appears to be synergistic and advantageous for the treatment of autoimmune diseases. 30279279

名称对应

Type IDs
Synonymous ALDD, D6S216, D6S216E, JMP, LMP7, NKJO, PRAAS1, PSMB5i, RING10
Gene
UniProtKB-ID: PSB8_HUMAN, X5CMJ9_HUMAN
UniprotKB: P28062, X5CMJ9
UniParc: UPI000002B1B1, UPI0000140B8A
EMBL: CR753889, BX088556, L11045, AL935043, AL669918, BX682530, KJ657696, CR762476, U32863, X62598, CT009502, U17496, KJ657697, AL671681, X66401, U32862, Z14982, U17497, BC001114, X87344, CH471081, BX927138
Ensembl: ENSG00000235715, ENSG00000206298, ENSG00000236443, ENSG00000230034, ENSG00000230669, ENSG00000204264, ENSG00000226201, ENSG00000231631
KO: hsa:5696
Nucleutide sequences
EMBL-CDS: AAA56777.1, CAA60786.1, AAH01114.1, AAA80234.1, CAA60787.1, CAA78705.1, CAA47026.1, EAX03644.1, AAA80235.1, EAX03645.1, CAA44482.1, AAA56778.1, CAA78706.1, AHW47959.1, AHW47976.1
Ensembl_TRS: ENST00000429645, ENST00000421445, ENST00000383238, ENST00000452573, ENST00000436627, ENST00000416134, ENST00000457261, ENST00000435978, ENST00000416564, ENST00000374882, ENST00000374881, ENST00000455660, ENST00000441960, ENST00000383236, ENST00000438442
Protein sequencees
Ensembl_PRO: ENSP00000364016, ENSP00000406797, ENSP00000364015, ENSP00000372725, ENSP00000372723, ENSP00000407539, ENSP00000394155, ENSP00000408825, ENSP00000412618, ENSP00000392693, ENSP00000397057, ENSP00000414731, ENSP00000404585, ENSP00000402406, ENSP00000414770
RefSeq: NP_683720.2, NP_004150.1
Others
UniRef100: UniRef100_P28062
UniRef90: UniRef90_P28062
UniRef50: UniRef50_P28062
UniGene: Hs.180062
CCDS: CCDS4757.1, CCDS4756.1

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