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10800 CYSLTR1

10800

CYSLTR1

cysteinyl leukotriene receptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition cysteinyl leukotriene receptor 1

研究结论

Date Results Publications
2021-01-23 12:59:00 Cysteinyl leukotriene receptor 1 promotes 5-fluorouracil resistance and resistance-derived stemness in colon cancer cells. 32474153
2021-01-16 15:56:00 Cysteinyl leukotriene receptor 1 modulates autophagic activity in retinal pigment epithelial cells. 33077798
2020-12-05 12:59:00 Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1. 32330496
2019-04-13 11:38:00 Drugs antagonizing the CysLT1 receptor, termed lukasts and typified by montelukast, are established therapeutics for clinical management of asthma.. Here we describe recent data indicating that montelukast may be used for prevention and treatment of AAA, thus representing a promising pharmacological tool for a deadly vascular disease with significant socio-economic impact. 30248405
2019-01-19 11:33:00 findings strongly implicate that cysLTR1 has the capacity to regulate cellular senescence in chondrocytes. It is suggested that montelukast may be a potential therapeutic agent for chondro-protective therapy. 29331588

名称对应

Type IDs
Synonymous CYSLT1, CYSLT1R, CYSLTR, HMTMF81
Gene
UniProtKB-ID: CLTR1_HUMAN, Q38Q91_HUMAN, Q38Q88_HUMAN
UniprotKB: Q9Y271, Q38Q91, Q38Q88
UniParc: UPI00005D3879, UPI00005D3878, UPI000003ACDF
EMBL: AF119711, DQ131799, DQ131800, AL445202, BC035750, CH471104, AK313643, DQ131803, AF133266, DQ131802, DQ131801, AY242130
Ensembl: ENSG00000173198
KO: hsa:10800
Nucleutide sequences
EMBL-CDS: AAD42285.1, AAO92297.1, BAG36401.1, EAW98598.1, AAD42778.1, EAW98599.1, AAH35750.1, ABA01565.1, ABA01564.1, ABA01563.1, ABA01566.1, ABA01567.1
Ensembl_TRS: ENST00000373304, ENST00000614798
Protein sequencees
Ensembl_PRO: ENSP00000362401, ENSP00000478492
RefSeq: NP_001269116.1, NP_006630.1, NP_001269117.1, NP_001269115.1
Others
UniRef100: UniRef100_Q38Q91, UniRef100_Q9Y271
UniRef90: UniRef90_Q38Q91, UniRef90_Q9Y271
UniRef50: UniRef50_Q9Y271, UniRef50_Q99JA4
UniGene: Hs.733809
CCDS: CCDS14439.1

全选

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