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A kinetic model of oxygen regulation of cytochrome production in Escherichia coli.

J. Theor. Biol.2006 Oct 7;242(3):547-63. Epub 2006 Apr 28
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摘要


Recent experimental work has identified the principal components arrayed by Escherichia coli in its sensing of, and response to, varying levels of oxygen. This apparatus may be leveraged/modified by the metabolic engineer to identify nonuniform oxygen and glucose regimens that deliver better yields than their uniform counterparts. Toward this end we build and analyse a mathematical model that captures the role played by oxygen in the regulation of cytochrome production in E. coli.

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