| Type | Description |
|---|---|
| Definition | DNA-binding transcriptional dual regulator ArcA |
| Date | Results | Publications |
|---|---|---|
| 2019-11-16 10:51:00 | The results suggest that deletion of arcA, iclR, and tdcC could efficiently increase l-threonine production in E. coli. | 31177569 |
| 2019-09-28 11:32:00 | These data reveal the cooperativity of TraJ and ArcA during F plasmid PY promoter activation and provide insights into the regulatory circuit controlling F-family plasmid-mediated bacterial conjugation. | 30322855 |
| 2019-07-13 11:14:00 | Study reports the in-situ structure of the E. coli AcrAB-TolC multidrug efflux pump obtained by electron cryo-tomography. The fully assembled efflux pump is observed in a closed state under conditions of antibiotic challenge and in an open state in the presence of AcrB inhibitor. Also study observed intermediate AcrAB complexes without TolC and discover that AcrA contacts the peptidoglycan layer of the periplasm. | 31201302 |
| 2019-06-29 11:04:00 | increased lag phases of ArcA overexpression strains, respiratory energy metabolism may be related to a general preparatory response, observed for decreasing growth rates, but with limited advantages for maximizing steady-state growth rate. | 28928483 |
| 2018-01-06 11:56:00 | The authors report the near-atomic resolution cryoEM structures of the Escherichia coli AcrAB-TolC multidrug efflux pump in resting and drug transport states, revealing a quaternary structural switch that allosterically couples and synchronizes initial ligand binding with channel opening. | 28355133 |
| Type | IDs |
|---|---|
| Synonymous | ECK4393, cpxC, dye, fexA, msp, seg, sfrA |
| Gene |
UniProtKB-ID:
ARCA_ECOLI
UniprotKB:
P0A9Q1
UniParc:
UPI0000125D8C
EMBL:
U00096,
L34010,
AP009048,
U14003,
M10044
EnsemblGenome:
b4401,
BAE78390
KO:
eco:b4401,
ecj:JW4364
|
| Nucleutide sequences |
EMBL-CDS:
AAA97297.1,
AAC77354.1,
AAA23476.1,
BAE78390.1,
AAA23718.1
EnsemblGenome_TRS:
AAC77354,
BAE78390
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE78390,
AAC77354
RefSeq:
NP_418818.1
|
| Others |
UniRef100:
UniRef100_P0A9Q3
UniRef90:
UniRef90_P0A9Q3
UniRef50:
UniRef50_P44918
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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