rnpA - RNase P protein component-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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948215 rnpA

基因描述

Type	Description
Definition	RNase P protein component

研究结论

Date	Results	Publications
2019-08-24 11:51:00	The results demonstrate that directional processing is an intrinsic property of RNase P and show how RNA sequence and structure context can modulate reaction rates in order to direct precursors along specific pathways.	30496557
2017-11-04 11:56:00	findings demonstrate the rph-1 mutation leads to synthesis of a truncated functionally inactive RNase PH protein that interferes with the 5'-end maturation of specific tRNAs with short 5' leaders by RNase P in the absence of RppH an RNA pyrophosphohydrolase that converts primary 5' triphosphates into 5' monophosphates; data indicate the presence of the triphosphate interferes with RNase P binding to the pre-tRNA	28808133
2017-10-21 11:47:00	The comparative biology of Escherichia coli RNase P and Arabidopsis thaliana PRORP isozymes has been reported.	28499021
2015-02-28 12:52:00	The ability of RNase P to initiate tRNA processing at the 3' ends of long primary transcripts by endonucleolytically removing the Rho-independent transcription terminator represents a previously unidentified function for the enzyme.	25183518
2013-11-30 10:47:00	Rules govern substrate recognition by C5, which reveal specificity that is hidden in cellular substrates for RNase P; nonspecific and specific RNA-binding modes may not differ fundamentally, but represent distinct parts of common affinity distributions.	24056935

名称对应

Type	IDs
Synonymous	ECK3696
Gene	UniProtKB-ID: RNPA_ECOLI UniprotKB: P0A7Y8 UniParc: UPI0000134428 EMBL: X01861, L10328, AP009048, U00096, M11056 EnsemblGenome: BAE77590, b3704 KO: eco:b3704, ecj:JW3681
Nucleutide sequences	EMBL-CDS: AAC76727.1, AAA24567.1, AAA62055.1, BAE77590.1, CAA25983.1 EnsemblGenome_TRS: AAC76727, BAE77590
Protein sequencees	EnsemblGenome_PRO: AAC76727, BAE77590 RefSeq: NP_418159.1
Others	UniRef100: UniRef100_A7ZTR0 UniRef90: UniRef90_B2VCE5 UniRef50: UniRef50_Q7M7H7

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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全选

Pubmed编号	文献信息	发表日期	相关基因
30496557	Distributive enzyme binding controlled by local RNA context results in 3' to 5' directional processing of dicistronic tRNA precursors by Escherichia coli ribonuclease P. Nucleic Acids Res. Jing Zhao , Michael E Harris	2019-02-20	-
28808133	The rph-1-Encoded Truncated RNase PH Protein Inhibits RNase P Maturation of Pre-tRNAs with Short Leader Sequences in the Absence of RppH. J. Bacteriol. Katherine E Bowden , Nicholas S Wiese , Tariq Perwez , Bijoy K Mohanty , Sidney R Kushner	2017-11-15	-
28499021	Protein-only RNase P function in Escherichia coli: viability, processing defects and differences between PRORP isoenzymes. Nucleic Acids Res. Markus GÃ¶Ãringer , Marcus Lechner , Nadia Brillante , Christoph Weber , Walter Rossmanith , Roland K Hartmann	2017-07-07	-
24561554	The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. Seesandra V Rajagopala , Patricia Sikorski , Ashwani Kumar , Roberto Mosca , James Vlasblom , Roland Arnold , Jonathan Franca-Koh , Suman B Pakala , Sadhna Phanse , Arnaud Ceol , Roman HÃ¤user , Gabriella Siszler , Stefan Wuchty , Andrew Emili , Mohan Babu , Patrick Aloy , Rembert Pieper , Peter Uetz	2014-03-01	-
25183518	Processing of the seven valine tRNAs in Escherichia coli involves novel features of RNase P. Nucleic Acids Res. Ankit Agrawal , Bijoy K Mohanty , Sidney R Kushner	2014-01-01	rnpA
24056935	Hidden specificity in an apparently nonspecific RNA-binding protein. Nature Ulf-Peter Guenther , Lindsay E Yandek , Courtney N Niland , Frank E Campbell , David Anderson , Vernon E Anderson , Michael E Harris , Eckhard Jankowsky	2013-10-17	rnpA
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
19932118	Protein-precursor tRNA contact leads to sequence-specific recognition of 5' leaders by bacterial ribonuclease P. J Mol Biol Kristin S Koutmou , Nathan H Zahler , Jeffrey C Kurz , Frank E Campbell , Michael E Harris , Carol A Fierke	2010-02-12	-
19917291	Binding of C5 protein to P RNA enhances the rate constant for catalysis for P RNA processing of pre-tRNAs lacking a consensus (+ 1)/C(+ 72) pair. J. Mol. Biol. Lei Sun , Frank E Campbell , Lindsay E Yandek , Michael E Harris	2010-02-05	rnpB, rnpA
19906695	Processing of the Escherichia coli leuX tRNA transcript, encoding tRNA(Leu5), requires either the 3'-->5' exoribonuclease polynucleotide phosphorylase or RNase P to remove the Rho-independent transcription terminator. Nucleic Acids Res Bijoy K Mohanty , Sidney R Kushner	2010-01-01	-

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