| Type | Description |
|---|---|
| Definition | V-set pre-B cell surrogate light chain 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-12 11:46:00 | Irrespective of subtype, Acute Lymphoblastic Leukemia with high levels of IGHM, IGLL1 and VPREB1 are arrested at the pre-B stage and correlate with good prognosis in high-risk pediatric B-cell precursor acute lymphoblastic leukemia. | 27611867 |
| 2014-03-08 10:13:00 | VPREB1 focal deletions are common in B-ALL and occur independent of V(D)J light chain recombination. Focal deletions of VPREB1 correlate with decreased expression levels and high-risk patients with focal deletions tend to have poorer overall survival | 23881307 |
| 2011-08-13 10:49:00 | The proportion of the individuals with <2 copies of the VPREB1 gene was significantly higher in the patient group than that in the controls, while that of the individuals with >2 copies was lower in the patient group than that in the controls. | 21144590 |
| 2010-04-07 21:40:00 | Observational study of gene-disease association. (HuGE Navigator) | 20237496 |
| 2010-01-21 00:00:00 | The 5' region of the VpreB gene contains a promoter which displays higher relative activity in preB cells compared with cells at other stages or from other lineages. | 11994467 |
| Type | IDs |
|---|---|
| Synonymous | CD179a, IGI, IGVPB, VPREB |
| Gene |
UniProtKB-ID:
VPREB_HUMAN,
F8W8C9_HUMAN
UniprotKB:
P12018,
F8W8C9
UniParc:
UPI0000138CF8,
UPI0001611018
EMBL:
CR456609,
M34927,
AC245060,
S74019,
D86992,
CH471095,
D88270
Ensembl:
ENSG00000169575
KO:
hsa:7441
|
| Nucleutide sequences |
EMBL-CDS:
AAB32118.1,
BAA19987.1,
AAA61292.1,
BAA20030.1,
EAW59498.1,
CAG30495.1
Ensembl_TRS:
ENST00000403807,
ENST00000302273
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000385361,
ENSP00000304590
RefSeq:
NP_001290438.1,
NP_009059.1
|
| Others |
UniRef100:
UniRef100_F8W8C9,
UniRef100_P12018
UniRef90:
UniRef90_P12018,
UniRef90_H2QLB7
UniRef50:
UniRef50_A0A3Q2H305,
UniRef50_P13372
UniGene:
Hs.247979
CCDS:
CCDS13798.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30349055 |
Nat Commun Yujing Li , Yunhua Liu , Hanchen Xu , Guanglong Jiang , Kevin Van der Jeught , Yuanzhang Fang , Zhuolong Zhou , Lu Zhang , Michael Frieden , Lifei Wang , Zhenhua Luo , Milan Radovich , Bryan P Schneider , Yibin Deng , Yunlong Liu , Kun Huang , Bin He , Jin Wang , Xiaoming He , Xinna Zhang , Guang Ji , Xiongbin Lu |
2018-10-22 | - |
| 27611867 |
PLoS One Dongfeng Chen , Junxiong Zheng , Natalija Gerasimcik , Kristina Lagerstedt , Helene Sjögren , Jonas Abrahamsson , Linda Fogelstrand , Inga-Lill Mårtensson |
2016-01-01 | - |
| 23881307 |
Leukemia D S Mangum , J Downie , C C Mason , M S Jahromi , D Joshi , V Rodic , M Müschen , N Meeker , N Trede , J K Frazer , Y Zhou , C Cheng , S Jeha , C-H Pui , C L Willman , R C Harvey , S P Hunger , J J Yang , P Barnette , C G Mullighan , R R Miles , J D Schiffman |
2014-01-01 | - |
| 24024966 |
Genome-wide association study of chronic periodontitis in a general German population. J. Clin. Periodontol. Alexander Teumer , Birte Holtfreter , Uwe Völker , Astrid Petersmann , Matthias Nauck , Reiner Biffar , Henry Völzke , Heyo K Kroemer , Peter Meisel , Georg Homuth , Thomas Kocher |
2013-11-01 |
PDCD6IP,
ST20-MTHFS,
CDH13,
LOC101927025,
LOC101927661,
LOC101928114,
LOC101928134,
LOC102724761,
MTHFS,
CHD1,
PTPRT,
GPN1,
C1orf87,
WDR36,
NRSN1,
PSMA8,
ZNF524,
CCDC13,
NKAIN2,
FAM47A,
ZNF579,
PARP15,
DEFA1,
C10orf91,
ADAMTS15,
ABCA1,
EPHA3,
ETS2,
NLGN1,
DKK1,
KDM4B,
NPAP1,
FRG1,
ERC2,
DAOA,
LINC00907,
SUMF1,
NKAIN3,
GRIK1,
LRP12,
HLA-DOA,
FOXA1,
BIRC5,
C12orf74,
HMX3,
IGF2R,
IGL,
KCNJ16,
FAM180A,
LBP,
ST20,
LOC400867,
NPM1P2,
FAM135B,
PIK3C3,
LRP1B,
ETAA1,
RBFOX1,
PGPEP1,
ETNK2,
NMUR2,
RGMA,
ERGIC1,
PTEN,
SEMA6A,
RIT2,
ROBO2,
RYR3,
BCORL1,
SCN2A,
BLK,
SETMAR,
CSMD1,
MFSD1,
SMURF2,
PRB2,
SNRPN,
SNTB1,
SS18,
TGIF1,
TIMP2,
ROCK1P1,
VPREB1,
ZNF385D,
THSD4,
CAMK4,
LINC00208,
RAB6C,
FAM126A,
FIZ1,
WDR73,
ITGA8,
ACTN1,
ACTN2,
MBD2,
HS6ST2,
IQSEC1
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21144590 |
The potential role of VPREB1 gene copy number variation in susceptibility to rheumatoid arthritis. Mol Immunol Seon-Hee Yim , Yeun-Jun Chung , Eun-Heui Jin , Seung-Cheol Shim , Ji-Young Kim , Yong-Shin Kim , Hae-Jin Hu , Seung-Hun Shin , Hyun-Ock Pae , Moncef Zouali , Hun-Tag Chung |
2011-06-01 | - |
| 20237496 |
New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun. S Davila , F E M Froeling , A Tan , C Bonnard , G J Boland , H Snippe , M L Hibberd , M Seielstad |
2010-04-01 |
SH2B3,
MICA,
NR1H3,
TSPAN2,
NAMPT,
PRG4,
KLRG1,
CD96,
EFS,
APC2,
LAMC3,
CRISP3,
TLR6,
CLEC10A,
SEMA4D,
CEBPG,
PROCR,
PRDX4,
IFI44,
CXCL13,
GNLY,
COLEC10,
SH2B2,
CD226,
TNFSF13B,
NFAT5,
KLRA1P,
CFHR4,
CFHR3,
C1QL1,
EDAR,
MAGED2,
PRDX3,
IFI44L,
LILRB5,
LILRB4,
LILRA1,
LILRA2,
DUS4L,
ESM1,
FGFR1OP,
FAF1,
CD160,
RASSF1,
IRAK3,
IL17F,
CHRM1,
CD300A,
COPE,
KIF12,
CMTM1,
SIGLEC11,
NLRP3,
TIRAP,
PGLYRP2,
PGLYRP3,
SLAMF6,
FCRL1,
FCRL3,
GBP4,
GBP5,
TNFRSF13C,
FOXP4,
IL22RA2,
DEFB118,
CLC,
ADD1,
SFXN4,
IFI27L1,
CCR3,
CCR4,
CCR5,
CCR7,
CCR8,
ACKR2,
CMKLR1,
CCDC78,
CD300LB,
OSCAR,
ANKLE1,
GABPB2,
CNTFR,
COL4A3,
COL4A4,
BPIFB6,
ZPLD1,
KLF6,
IL31RA,
PPARGC1B,
RAET1E,
ADORA2B,
SSC4D,
CR1,
PXDNL,
CR2,
CREB1,
CREM,
GAB3,
CRP
|
| 17474147 |
Proteomics Chenggang Wu , Mike Haiting Ma , Kevin R Brown , Matt Geisler , Lei Li , Eve Tzeng , Christina Y H Jia , Igor Jurisica , Shawn S-C Li |
2007-06-01 |
HDAC6,
HCN4,
CHAF1A,
CDH11,
PRG4,
HNRNPR,
SF3B4,
EFS,
TRAIP,
SEC24B,
RPP38,
CENPA,
TGOLN2,
CELF2,
PNMA2,
ZNF274,
EHMT2,
FASTK,
BAZ2A,
MAP4K5,
MAP4K1,
AKAP2,
NXPH3,
GPR45,
CSMD2,
OSBPL5,
CNTFR,
UHMK1,
DUSP15,
ALS2CR12,
CRK,
CRYBB3,
CSF2RA,
DAB2,
DAG1,
DARS,
GSX2,
ASXL1,
DLG4,
DLX4,
DNM1,
AGER,
DNASE1L2,
DNM2,
DOCK1,
DOCK3,
ABAT,
DTX1,
ECT2,
EFNA5,
CELSR3,
CELSR2,
AHSG,
ELK3,
EPS15,
EXTL1,
EXTL3,
F2RL2,
FANCA,
FCGR2B,
DLGAP4,
CD93,
SHANK2,
FOXF2,
TPX2,
RIMS1,
SPEN,
FOXJ1,
TNIK,
CUL9,
NFASC,
EPB41L3,
FLNA,
FLNB,
FLNC,
VPS13A,
SASH1,
AFF2,
ADNP,
BRD4,
TGDS,
CD2AP,
NR5A1,
ABL1,
FYB,
FYN,
GABBR1,
GABRA3,
GAD1,
NELFB,
MYRIP,
DNM3,
OPTC,
HIBCH,
GCDH,
GHR,
NBEA,
RPUSD2,
DKKL1
|
| 16818733 |
J. Immunol. Benjamin Rossi , Marion Espeli , Claudine Schiff , Laurent Gauthier |
2006-07-15 | - |
| 15461802 |
A genome annotation-driven approach to cloning the human ORFeome. Genome Biol. John E Collins , Charmain L Wright , Carol A Edwards , Matthew P Davis , James A Grinham , Charlotte G Cole , Melanie E Goward , Begoña Aguado , Meera Mallya , Younes Mokrab , Elizabeth J Huckle , David M Beare , Ian Dunham |
2004-01-01 |
CHKB-AS1,
HMGXB4,
TOM1,
LOC400927-CSNK1E,
SF3A1,
CACNG2,
SLC25A17,
DDX17,
RFPL3S,
RFPL3,
RFPL2,
RFPL1S,
NUP50,
TOB2,
KDELR3,
IFT27,
CDC42EP1,
DMC1,
RABL2B,
RABL2A,
CHEK2,
CHKB,
PACSIN2,
USP18,
PHF21B,
PIK3IP1,
C1QTNF6,
C22orf39,
TANGO2,
EMID1,
ANKRD54,
COMT,
ADORA2A,
CRKL,
APOBEC3D,
ZNF280B,
CRYBA4,
CRYBB1,
CRYBB2,
CRYBB3,
CSF2RB,
CSNK1E,
CCT8L2,
LINC00896,
AIFM3,
C22orf15,
HSCB,
CCDC117,
HORMAD2,
DUSP18,
C22orf42,
ENTHD1,
DNAJB7,
FAM109B,
NFAM1,
CDPF1,
GTSE1-AS1,
CYP2D6,
ADSL,
AP1B1,
TMPRSS6,
APOBEC3H,
WBP2NL,
DDT,
POLR3H,
CYB5R3,
APOBEC3A,
APOBEC3F,
EWSR1,
MORC2,
HIC2,
GRAMD4,
TTLL12,
MLC1,
KIAA0930,
PES1,
PRAME,
SEC14L2,
RBFOX2,
SEZ6L,
RASD2,
PATZ1,
SH3BP1,
TSSK2,
SDF2L1,
PPIL2,
PITPNB,
PISD,
IL17RA,
BRD1,
BCL2L13,
TFIP11,
PRR14L,
SERHL2,
XRCC6,
TMEM211,
C22orf31,
TBC1D22A,
CBY1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
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目前还没有研究热点人员