| Type | Description |
|---|---|
| Definition | jumonji domain containing 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:29:00 | Aberrant JmjC domain-containing protein 8 (JMJD8) expression promotes activation of AKT and tumor epithelial-mesenchymal transition. | 32879443 |
| 2020-03-21 12:40:00 | The research provided data to establish the role of JMJD8 in regulating tumor cell proliferation and their sensitivity to ionizing irradiation or chemo-therapy drug, and the AKT/NF-kappaB/COX-2 signaling mediated expression of Ku70/Ku80 was involved. | 31473257 |
| 2019-07-27 10:55:00 | Study demonstrated that JMJD8 is the first JmjC domain-containing protein found in the lumen of the endoplasmic reticulum that may function in protein complex assembly and protein folding. | 29133832 |
| 2017-06-24 12:29:00 | Jmjd8 is upregulated during endothelial differentiation and regulates endothelial sprouting and metabolism by interacting with pyruvate kinase M2. | 27199445 |
| Type | IDs |
|---|---|
| Synonymous | C16orf20, PP14397 |
| Gene |
UniProtKB-ID:
JMJD8_HUMAN
UniprotKB:
Q96S16
UniParc:
UPI0001892CE3,
UPI00001C1FBF
EMBL:
Z92544,
BC073785,
BC137100,
BC137101,
BC094850,
AE006464,
DQ074695,
CH471112,
AF370420
Ensembl:
ENSG00000161999
KO:
hsa:339123
|
| Nucleutide sequences |
EMBL-CDS:
AAH94850.1,
AAI37102.1,
AAY82251.1,
AAQ15256.1,
EAW85755.1,
AAI37101.1,
AAH73785.1,
EAW85754.1,
AAK61243.1
Gene_ORFName:
PP14397
Ensembl_TRS:
ENST00000609261,
ENST00000562824
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000454358,
ENSP00000477481
RefSeq:
NP_001310849.2,
NP_001310848.2,
NP_001310847.2,
NP_001005920.3,
NP_001310851.2
|
| Others |
UniRef100:
UniRef100_Q96S16
UniRef90:
UniRef90_Q96S16
UniRef50:
UniRef50_Q96S16
UniGene:
Hs.533771
CCDS:
CCDS45369.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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