| Type | Description |
|---|---|
| Definition | integrin subunit beta 6 |
| Date | Results | Publications |
|---|---|---|
| 2016-05-28 10:25:00 | These data support the hypothesis that IL-1beta was initially induced by hyperoxia; alphavbeta6 subsequently interacted with and activated TGF-beta1. | 26279426 |
| 2013-07-20 11:53:00 | Integrin alphavbeta6 is strongly induced de novo in newly formed bile ducts because of cholangiocyte proliferation during ischemia-related biliary fibrogenesis after liver transplantation. | 23422496 |
| 2013-02-09 10:31:00 | Lysophosphatidic acid signals through LPA2 receptors and Galphaq proteins of cultured proximal tubule cells to transactivate latent TGF-beta in a Rho/Rho-kinase and alphavbeta6 integrin-dependent manner. | 22885106 |
| 2011-12-09 11:09:00 | Integrin alphavbeta6 is induced de novo in rodent and human liver fibrosis, where it is expressed on activated bile duct epithelia and (transitional) hepatocytes during fibrosis progression. | 18221819 |
| 2010-01-21 00:00:00 | Integrin alphavbeta6 is strongly up-regulated in proliferating bile duct epithelia and drives fibrogenesis via adhesion to fibronectin and auto/paracrine TGF-beta1 activation. | 18538673 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ITB6_RAT
UniprotKB:
Q6AYF4
UniParc:
UPI000021D61B
EMBL:
BC079069
Ensembl:
ENSRNOG00000008346
KO:
rno:311061
|
| Nucleutide sequences |
EMBL-CDS:
AAH79069.1
Ensembl_TRS:
ENSRNOT00000011030,
ENSRNOT00000086576
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000011030,
ENSRNOP00000074271
RefSeq:
XP_008760068.1,
XP_006234295.1,
XP_017447175.1,
XP_008760067.1,
XP_006234294.1,
NP_001004263.1
|
| Others |
UniRef100:
UniRef100_Q6AYF4
UniRef90:
UniRef90_Q6AYF4
UniRef50:
UniRef50_P18564
UniGene:
Rn.19828
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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