| Type | Description |
|---|---|
| Definition | transient receptor potential cation channel, subfamily M, member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 15:59:00 | The effects of TRPM2, TRPM6, TRPM7 and TRPM8 gene expression in hepatic ischemia reperfusion injury. | 31002158 |
| 2020-05-02 11:26:00 | TRPM2 participates in the transformation of acute pain to chronic pain during injury-induced neuropathic pain | 31120580 |
| 2019-08-17 10:51:00 | Results suggest that the mechanisms of fibromyalgia may be mediated via the TRPM2 and TRPV1 channels by inducing mitochondrial apoptosis, and pain in the sciatic and dorsal root ganglion. However, the pain, oxidant, and apoptotic effects of fibromyalgia were reversed through the blockage of TRPM2 and TRPV1 in the neurons by Se treatment. | 29235496 |
| 2018-12-22 11:08:00 | TRPM2 was most highly expressed in microglia with little expression in neurons and astrocytes | 29842890 |
| 2018-07-28 11:51:00 | these findings supported the role of TRPM2 channel in reactive oxygen species-induced NLRP3 activation in microglial cells through the exposure to Amyloid-beta | 29107864 |
| Type | IDs |
|---|---|
| Synonymous | Trpm2-predicted |
| Gene |
UniProtKB-ID:
TRPM2_RAT
UniprotKB:
E9PTA2
UniParc:
UPI0001B79AA5
EMBL:
AABR07044581,
AB193179,
AABR07072820,
AC109383,
AY749166,
AABR07044580
Ensembl:
ENSRNOG00000001216
KO:
rno:294329
|
| Nucleutide sequences |
EMBL-CDS:
AAW65801.1,
BAE72117.1
Ensembl_TRS:
ENSRNOT00000001631
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000001631
RefSeq:
NP_001011559.1,
XP_017457095.1,
XP_008771033.1,
XP_017457094.1,
XP_017457093.1,
XP_017457092.1,
XP_006256311.1,
XP_006256310.1
|
| Others |
UniRef100:
UniRef100_E9PTA2
UniRef90:
UniRef90_E9PTA2
UniRef50:
UniRef50_O94759
UniGene:
Rn.214495
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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