| Type | Description |
|---|---|
| Definition | DNA topoisomerase II |
| Date | Results | Publications |
|---|---|---|
| 2017-09-23 12:25:00 | Rrp2 possesses SUMO-binding ability and prevents excessive Top2 degradation by competing against the SUMO-targeted ubiquitin ligase (STUbL) for SUMO chain binding and by displacing SUMOylated Top2 from DNA. | 28552615 |
| 2011-12-17 11:59:00 | DNA topoisomerase 2 mutant allele mildly delays the mitotic progression and activates the checkpoint protein kinase Chk1 in fission yeast Schizosaccharomyces pombe. | 21767457 |
| 2010-01-21 00:00:00 | Schizosaccharomyces pombe Rad32(Mre11) nuclease activity is involved in the removal of both Top2 from 5' DNA ends as well as Top1 from 3' ends in vivo and a ctp1(CtIP) deletion is defective for Top2 removal but overproficient for Top1 removal. | 19150433 |
| 2010-01-21 00:00:00 | topoisomerase II has a role in disentangling dysfunctional telomeres | 19680223 |
| Type | IDs |
|---|---|
| Synonymous | ptr11 |
| Gene |
UniProtKB-ID:
TOP2_SCHPO
UniprotKB:
P08096
UniParc:
UPI0000137163
EMBL:
CU329671,
X04326
EnsemblGenome:
SPBC1A4.03c
KO:
spo:SPBC1A4.03c
|
| Nucleutide sequences |
EMBL-CDS:
CAA27857.1,
CAA20107.1
Gene_ORFName:
SPBC1A4.03c
EnsemblGenome_TRS:
SPBC1A4.03c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPBC1A4.03c.1:pep
RefSeq:
NP_595805.1
|
| Others |
UniRef100:
UniRef100_P08096
UniRef90:
UniRef90_P08096
UniRef50:
UniRef50_P08096
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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