| Type | Description |
|---|---|
| Definition | fucosyltransferase 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:29:00 | Using Eukaryotic Expression Systems to Generate Human alpha1,3-Fucosyltransferases That Effectively Create Selectin-Binding Glycans on Stem Cells. | 32901486 |
| 2019-12-21 10:15:00 | Overexpressed N-fucosylation on cell surface promotes the migration and invasion of metastatic pancreatic cancer cells. Overexpressed N-fucosylation is driven by gene FUT3, 5, and 6 in metastatic pancreatic cancer cells. | 30808544 |
| 2019-09-07 11:57:00 | findings indicated that HOTAIR/miR-326/FUT6 axis mediated colorectal cancer (CRC) procession through alpha1, 3-fucosylated CD44 via PI3K/AKT/mTOR pathway. This work rendered new therapeutic targets for CRC. | 30742932 |
| 2019-07-20 13:10:00 | we identified a novel association of a common loss-of-function, missense variant in Fucosyltransferase 6 (FUT6; rs17855739,p.Glu274Lys, P = 9.02 x 10-24) with higher soluble E-selectin levels. This variant is considerably more common in populations of African ancestry compared to non-African ancestry populations. | 30307499 |
| 2018-04-21 11:51:00 | data suggest that both FUT5 and FUT6 can promote the development of colorectal cancer (CRC) via the PI3K/Akt signalling pathway, which is regulated by miR-125a-3p. miR-125a-3p may serve as a predictive biomarker and a potential therapeutic target in CRC treatment. | 28771224 |
| Type | IDs |
|---|---|
| Synonymous | FCT3A, FT1A, Fuc-TVI, FucT-VI |
| Gene |
UniProtKB-ID:
FUT6_HUMAN,
Q6P7E6_HUMAN
UniprotKB:
P51993,
Q6P7E6
UniParc:
UPI000012ADAC,
UPI000016A1E5,
UPI0000223FE7
EMBL:
AF131211,
U27337,
U27336,
U27335,
M98825,
BC061700,
U27333,
L01698,
CH471139,
U27332,
U27334,
U27331,
AL031258
Ensembl:
ENSG00000156413
KO:
hsa:2528
|
| Nucleutide sequences |
EMBL-CDS:
EAW69136.1,
AAC50195.1,
AAA99222.1,
EAW69137.1,
AAB03078.1,
AAC50192.1,
AAC50193.1,
AAC50196.1,
EAW69139.1,
AAC50190.1,
EAW69138.1,
AAD33509.1,
AAC50191.1,
AAC50194.1,
AAH61700.1
Ensembl_TRS:
ENST00000527106,
ENST00000318336,
ENST00000286955,
ENST00000524754,
ENST00000592563
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000431708,
ENSP00000313398,
ENSP00000286955,
ENSP00000432954,
ENSP00000466016
RefSeq:
NP_001368885.1,
NP_001368887.1,
NP_001356431.1,
NP_000141.1,
NP_001356434.1,
NP_001368886.1,
NP_001368884.1,
XP_011526174.1,
XP_011526177.1,
NP_001035791.1,
NP_001368888.1,
NP_001356433.1
|
| Others |
UniRef100:
UniRef100_Q6P7E6,
UniRef100_P51993
UniRef90:
UniRef90_P51993
UniRef50:
UniRef50_P21217
UniGene:
Hs.631846,
Hs.705615
CCDS:
CCDS12152.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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