| Type | Description |
|---|---|
| Definition | selenophosphate synthetase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:15:00 | Structural analysis of human SEPHS2 protein, a selenocysteine machinery component, over-expressed in triple negative breast cancer. | 31695102 |
| 2017-06-24 11:26:00 | Data confirm interactions among components of the early steps of the selenocysteine biosynthesis pathway (SEPSECS, SECP43, SEPHS1, and SEPHS2); SECP43, which interacts with SEPSECS and SEPHS1, is a globular protein that forms oligomers in vivo. | 28414460 |
| 2014-09-06 11:00:00 | miR-185 plays a role in up-regulation of GPX2 and SEPHS2 expression.In the case of SEPHS2 this may contribute to maintaining selenoprotein synthesis. | 23934683 |
| 2010-01-21 00:00:00 | the Sps1-encoded enzyme depends on a selenium salvage system that recycles l-selenocysteine, whereas the Sps2 enzyme can function with a selenite assimilation system | 15534230 |
| Type | IDs |
|---|---|
| Synonymous | SPS2 |
| Gene |
UniProtKB-ID:
SPS2_HUMAN
UniprotKB:
Q99611
UniParc:
UPI00001678A0
EMBL:
U43286,
BC016643,
AC116348,
BC002381
Ensembl:
ENSG00000179918
KO:
hsa:22928
|
| Nucleutide sequences |
EMBL-CDS:
AAH02381.3,
AAC50958.2,
AAH16643.1
Ensembl_TRS:
ENST00000478753
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000418669
RefSeq:
NP_036380.2
|
| Others |
UniRef100:
UniRef100_Q99611
UniRef90:
UniRef90_Q99611
UniRef50:
UniRef50_P97364
UniGene:
Hs.118725
CCDS:
CCDS42150.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31695102 |
Sci Rep Carmine Nunziata , Andrea Polo , Angela Sorice , Francesca Capone , Marina Accardo , Eliana Guerriero , Federica Zito Marino , Michele Orditura , Alfredo Budillon , Susan Costantini |
2019-11-06 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 28414460 |
Biochemistry Flore Oudouhou , Bastien Casu , Arnold Steve Dopgwa Puemi , Jurgen Sygusch , Christian Baron |
2017-05-02 | - |
| 27645994 |
Selenoprotein Gene Nomenclature. J Biol Chem Vadim N Gladyshev , Elias S Arnér , Marla J Berry , Regina Brigelius-Flohé , Elspeth A Bruford , Raymond F Burk , Bradley A Carlson , Sergi Castellano , Laurent Chavatte , Marcus Conrad , Paul R Copeland , Alan M Diamond , Donna M Driscoll , Ana Ferreiro , Leopold Flohé , Fiona R Green , Roderic Guigó , Diane E Handy , Dolph L Hatfield , John Hesketh , Peter R Hoffmann , Arne Holmgren , Robert J Hondal , Michael T Howard , Kaixun Huang , Hwa-Young Kim , Ick Young Kim , Josef Köhrle , Alain Krol , Gregory V Kryukov , Byeong Jae Lee , Byung Cheon Lee , Xin Gen Lei , Qiong Liu , Alain Lescure , Alexei V Lobanov , Joseph Loscalzo , Matilde Maiorino , Marco Mariotti , K Sandeep Prabhu , Margaret P Rayman , Sharon Rozovsky , Gustavo Salinas , Edward E Schmidt , Lutz Schomburg , Ulrich Schweizer , Miljan SimonoviÄ , Roger A Sunde , Petra A Tsuji , Susan Tweedie , Fulvio Ursini , Philip D Whanger , Yan Zhang |
2016-11-11 | - |
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25798074 |
Proteome Sci Fernanda Luisa Basei , Gabriela Vaz Meirelles , Germanna Lima Righetto , Deivid Lucas Dos Santos Migueleti , Juliana Helena Costa Smetana , Jörg Kobarg |
2015-01-01 | - |
| 23934683 |
Mol Nutr Food Res Anabel Maciel-Dominguez , Daniel Swan , Dianne Ford , John Hesketh |
2013-12-01 |
SEPHS2,
GPX2,
MIR185
|
| 22939629 |
A census of human soluble protein complexes. Cell Pierre C Havugimana , G Traver Hart , Tamás Nepusz , Haixuan Yang , Andrei L Turinsky , Zhihua Li , Peggy I Wang , Daniel R Boutz , Vincent Fong , Sadhna Phanse , Mohan Babu , Stephanie A Craig , Pingzhao Hu , Cuihong Wan , James Vlasblom , Vaqaar-un-Nisa Dar , Alexandr Bezginov , Gregory W Clark , Gabriel C Wu , Shoshana J Wodak , Elisabeth R M Tillier , Alberto Paccanaro , Edward M Marcotte , Andrew Emili |
2012-08-31 |
SRB2,
TRA1,
MED6,
CDH2,
DDTL,
ABI1,
SRA1,
UQCRFS1P1,
SNRPGP15,
ZNF316,
LOC100132057,
PDCD6IP,
PDCD6,
MED16,
PIGK,
WASH1,
CHAF1A,
TOM1L1,
HMGXB4,
RANBP9,
SMC4,
UBA2,
SAE1,
FARSB,
ABCB6,
ABCF2,
TIMM23B,
SCAMP3,
DPP3,
HUWE1,
TSSC4,
PDCD7,
USH1C,
PQBP1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
TSFM,
PPIF,
ARPC2,
RAD50,
PREB,
ACTR1B,
ACTR1A,
RASGRP1,
LRPPRC,
PDIA6,
TRAP1,
RBM12,
G3BP1,
SUGP2,
TRIM28,
WASF2,
SLC25A13,
SORBS3,
ALYREF,
TXNDC9,
CDK4,
PRMT3,
PSME3,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
FLOT1,
PSMD14,
CDK7,
ADAM10,
PLIN3,
STX6,
MSLN,
HNRNPR,
MRPS31,
TIMM17B,
RIDA,
POP7,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
STUB1,
UBE4B,
BET1,
CWC27,
SAP18,
SMNDC1,
BCAS2,
EIF1B,
SF3A1,
MAEA,
KATNB1,
TCIRG1,
RTN3,
LANCL1
|
| 22658674 |
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell Alfredo Castello , Bernd Fischer , Katrin Eichelbaum , Rastislav Horos , Benedikt M Beckmann , Claudia Strein , Norman E Davey , David T Humphreys , Thomas Preiss , Lars M Steinmetz , Jeroen Krijgsveld , Matthias W Hentze |
2012-06-08 |
GNPDA1,
SCARNA27,
GABPB1-AS1,
NFYC-AS1,
FKSG29,
PHKA2-AS1,
HDAC6,
PDCD6,
C17orf96,
LOC100287042,
MIR3652,
ARPC4-TTLL3,
ATP5J2-PTCD1,
TGIF2-C20orf24,
FARSB,
ABCC5,
ABCF2,
HUWE1,
ARPC4,
ARPC1B,
ACTR3,
ACTR1A,
LRPPRC,
TRAP1,
BCAP31,
NAMPT,
RBM12,
TOB1,
G3BP1,
SUGP2,
MBNL2,
ABI2,
CEBPZ,
ATP6AP2,
SLC25A15,
RCL1,
RBM7,
RBM6,
RBM5,
ALYREF,
PSME3,
MPHOSPH10,
NUTF2,
USPL1,
DDX39A,
STX6,
HNRNPR,
MRPS31,
RIDA,
SF3B4,
AKAP8,
STUB1,
SIGMAR1,
SMNDC1,
BCAS2,
SF3A1,
CDKN2A,
APBB3,
SMYD5,
ADAR,
EMC8,
NPM3,
HMG20A,
NOD1,
RACK1,
NDC80,
NSA2,
YAP1,
CD2BP2,
TUBGCP3,
RBM14,
EMG1,
ACAA2,
PPIE,
TAB1,
MAD2L2,
PIBF1,
SLC25A17,
NXF1,
CREB3,
LRRC41,
SYNCRIP,
ENOX2,
MYBBP1A,
DDX17,
ADARB2,
CHERP,
HYOU1,
IPO8,
NOP56,
RNASEH2A,
GLRX3,
DCTN2,
LAMTOR5,
PRDX4,
AGPAT1,
RPP30,
SLU7,
MRPL28
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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