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20606 Sstr2

20606

Sstr2

somatostatin receptor 2

protein-coding

Mus musculus

基因描述

Type Description
Definition somatostatin receptor 2

研究结论

Date Results Publications
2020-10-24 14:07:00 Somatostatin Type 2 Receptor Antibody Enhances Mechanical Hyperalgesia in the Dorsal Root Ganglion Neurons after Sciatic Nerve-pinch Injury: Evidence of Behavioral Studies and Bax Protein Expression. 31686636
2020-05-16 11:02:00 is primarily expressed and colocalized intracellularly. Activation of 5 and CB1R protected huntingtin-mutant knock-in striatal neurons from quinolinic-acid-induced toxicity. Co-activation of and CB1R resulted in loss of protective effects, delayed ERK1/2 phosphorylation and altered receptor complex composition. 31381945
2019-04-20 10:29:00 Unpredictable chronic mild stress (UCMS) caused neuroendocrine changes, physical deteriorations, increased anxiety- and depressive-like behaviors and working memory impairments. sst2KO mice displayed behavioral alterations which were similar to stressed WT and exhibited exacerbated changes following UCMS exposure. The evaluations performed in the older mice showed significant long-term effects of UCMS exposure. 29409919
2019-03-23 12:02:00 is mainly expressed in distal tubules and collecting ducts in murine kidneys, and the expression of duanyu1942R2 decreases during cyst growth in two polycystic kidney disease mouse models 30261745
2018-03-24 11:53:00 Both hippocampal sst2 and sst4 receptors selectively inhibit stress-induced HPA axis activation but mediate anxiolytic and antidepressive effects through distinct mechanisms. 27986975

名称对应

Type IDs
Synonymous SRIF-1, SS2R, SSTR-2, Smstr-2, Smstr2, sst2
Gene
UniProtKB-ID: SSR2_MOUSE
UniprotKB: P30875
UniParc: UPI0000000A47, UPI00000295E9
EMBL: M81832, X68951, S71756, AF008914
Ensembl: ENSMUSG00000047904
KO: mmu:20606
Nucleutide sequences
EMBL-CDS: AAA58256.1, AAD01420.1, CAA48766.1, AAP20804.1, AAD01419.1
Ensembl_TRS: ENSMUST00000067591, ENSMUST00000106630, ENSMUST00000146390
Protein sequencees
Ensembl_PRO: ENSMUSP00000102241, ENSMUSP00000138101, ENSMUSP00000068578
RefSeq: NP_001036071.1, NP_033243.2
Others
UniRef100: UniRef100_P30875
UniRef90: UniRef90_P30874
UniRef50: UniRef50_P30874
CCDS: CCDS59571.1, CCDS25598.1

全选

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