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17002 Ltf

17002

Ltf

lactotransferrin

protein-coding

Mus musculus

基因描述

Type Description
Definition lactotransferrin

研究结论

Date Results Publications
2020-12-19 13:40:00 Distribution of Lactoferrin Is Related with Dynamics of Neutrophils in Bacterial Infected Mice Intestine. 32218351
2020-04-25 10:06:00 Lactoferrin can induce MDSCs differentiation and apoptosis, as well as upregulate TLR9 expression. TLR9 agonist or lactoferrin treatment can rescue this phenotype in the tumor metastasis mouse model. Our results suggest a protective role of lactoferrin in cancer metastasis, along with a deficiency in certain components of the innate immune system, may lead to a pro-metastatic tumor microenvironment. 31462711
2019-05-25 12:09:00 LTF mRNA was undetectable in the mouse brain, even after ICH. Unlike mRNA, LTF protein increased in ICH-affected hemispheres by 6 hours, peaked at 24 to 72 hours, and remained elevated for at least a week after ICH. At the single cell level, LTF was detected in in the hematoma-affected brain at all time points after ICH. We also found elevated LTF in the plasma after ICH. 29636422
2018-08-18 11:11:00 Hepatic Ltf prevents hepatic steatosis through inhibition of dietary lipid uptake in radiation-induced NAFLD mouse model. We also suggest coumestrol as a drug candidate for prevention of NAFLD. 29975946
2016-12-17 11:36:00 Data indicate that lactoferrin uptake across duodenum by glyceraldehyde-3-phosphate dehydrogenase (GAPDH). 26672975

名称对应

Type IDs
Synonymous Csp82, Lf, MMS10R, Ms10r
Gene
UniProtKB-ID: TRFL_MOUSE
UniprotKB: P08071
UniParc: UPI0000023AD4
EMBL: M74778, D88510, J03298, BC006904, AK144556, AK036491, AK151822
Ensembl: ENSMUSG00000032496
KO: mmu:17002
Nucleutide sequences
EMBL-CDS: AAA39427.1, AAA40525.1, BAE25936.1, BAE30719.1, AAH06904.1, BAC29450.1, BAA13633.1
Ensembl_TRS: ENSMUST00000035077
Protein sequencees
Ensembl_PRO: ENSMUSP00000035077
RefSeq: NP_032548.2
Others
UniRef100: UniRef100_P08071
UniRef90: UniRef90_P08071
UniRef50: UniRef50_P02788
UniGene: Mm.282359
CCDS: CCDS23581.1

全选

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