| Type | Description |
|---|---|
| Definition | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:29:00 | BK ablation attenuates osteoblast bone formation via integrin pathway. | 31570694 |
| 2019-09-21 12:19:00 | Tthe blockage of Cav1.2 increased the TC while reduced the iCa(2+) signal. Similar results were observed after the blockage of TRPs or BKCa. Therefore, caffeine promoted Ca(2+)-influx via TRPs and Cav1.2, and hyperpolarization through the activation of BKCa, inducing negative feedback of TC. | 31194991 |
| 2019-09-21 11:15:00 | Caveolae provide a key microdomain in renal collecting duct cells for coupling of TRPV4 with SK3, IK1, and BK that directly contributes to TRPV4-mediated Ca(2+) signaling in these domains. | 30207167 |
| 2019-08-10 10:53:00 | Caveolae play a critical role in protein targeting and preserving the close structural relationship between CaV3.2 and RyR needed to drive BKCa-mediated feedback control in resistance arteries. | 30354206 |
| 2019-07-13 10:41:00 | membrane potential-dependent regulation of L-type Ca(2+) channels appears to be important for histamine-, U46619-, and carbachol-induced phasic contractions in airway smooth muscle. Contractions can be abolished by BKCa channel openers, suggesting that these channels are potential targets for treating some causes of airway obstruction. | 30257105 |
| Type | IDs |
|---|---|
| Synonymous | 5730414M22Rik, BKCa, MaxiK, Slo, Slo1, mSlo, mSlo1 |
| Gene |
UniProtKB-ID:
KCMA1_MOUSE,
A0A087WRS4_MOUSE,
A0A087WQN5_MOUSE,
A0A286YDM6_MOUSE,
A0A087WQ41_MOUSE,
A0A286YD35_MOUSE,
Q3UXG3_MOUSE
UniprotKB:
Q08460,
A0A087WRS4,
A0A087WQN5,
A0A286YDM6,
A0A087WQ41,
A0A286YD35,
Q3UXG3
UniParc:
UPI0002380CEC,
UPI00003519EF,
UPI0000028549,
UPI00005ABBB9,
UPI0002380CE4,
UPI00003519EE,
UPI00003519EC,
UPI0000DBE6FB,
UPI0003D73C12,
UPI0002380CE8,
UPI00003519ED
EMBL:
L16912,
CT010582,
AC154420,
AF156674,
AC154593,
CT025624,
AF465244,
AK135652,
U09383,
AC154433,
AC154795
Ensembl:
ENSMUSG00000063142
KO:
mmu:16531
|
| Nucleutide sequences |
EMBL-CDS:
AAL69971.1,
AAA50215.1,
AAA39746.1,
AAD49225.1,
BAE22600.1
Ensembl_TRS:
ENSMUST00000188991,
ENSMUST00000188285,
ENSMUST00000224468,
ENSMUST00000190044,
ENSMUST00000145596
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000140751,
ENSMUSP00000140275,
ENSMUSP00000153312,
ENSMUSP00000140033,
ENSMUSP00000153247
RefSeq:
XP_006518665.1,
NP_034740.2,
XP_006518657.1,
XP_017171362.1,
XP_011243269.1,
XP_006518656.1,
XP_017171364.1,
NP_001240297.1,
NP_001240296.1,
XP_017171361.1,
XP_006518658.1,
XP_006518655.1,
NP_001240300.1,
XP_036014376.1,
NP_001240290.1,
NP_001240301.1,
NP_001240292.1,
NP_001240303.1,
XP_036014375.1,
NP_001240298.1,
XP_017171370.1,
XP_017171372.1,
NP_001240293.1,
XP_017171365.1,
NP_001240306.1,
NP_001240288.1,
XP_017171369.1,
XP_017171363.1,
XP_006518673.1,
NP_001240287.1,
XP_006518662.1,
XP_006518668.1,
NP_001240299.1,
NP_001240289.1,
NP_001240294.1,
XP_006518654.1,
XP_036014377.1,
NP_001240302.1,
XP_017171367.1,
XP_006518666.1,
NP_001240304.1,
XP_006518669.1,
NP_001240295.1,
NP_001240307.1,
XP_017171359.1,
XP_036014374.1,
NP_001240305.1,
NP_001240291.1
|
| Others |
UniRef100:
UniRef100_A0A087WQN5,
UniRef100_A0A286YDM6,
UniRef100_A0A286YD35,
UniRef100_Q3UXG3,
UniRef100_Q08460,
UniRef100_A0A087WRS4,
UniRef100_A0A087WQ41
UniRef90:
UniRef90_A0A087WRS4,
UniRef90_A0A087WQ41,
UniRef90_Q08460,
UniRef90_Q3UXG3,
UniRef90_A0A286YDM6
UniRef50:
UniRef50_Q3UXG3,
UniRef50_Q08460-4,
UniRef50_Q08460-2,
UniRef50_Q8AYS8,
UniRef50_Q08460
UniGene:
Mm.343607,
Mm.486347
CCDS:
CCDS79276.1,
CCDS79275.1,
CCDS79277.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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