| Type | Description |
|---|---|
| Definition | gamma-aminobutyric acid (GABA) A receptor, subunit delta |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 11:12:00 | Results suggest that GABAA([delta])R preferentially affects the anxiety-like behavior in open field test in a development-dependent manner, but only in female mice. | 31261237 |
| 2019-10-05 10:34:00 | Knockdown of Ttr in cultured cerebellar granule neurons significantly decreased the delta receptor expression; whereas overexpressing Ttr in cortical neurons increased the delta receptor expression. In vivo analysis of Ttr-/- mice revealed a significant decrease of the surface expression of the delta-GABAA-Rs in cerebellar granule neurons. Together, studies identified Ttr as a novel regulator of the delta-GABAA-Rs. | 30615651 |
| 2018-04-14 10:23:00 | Using mice with or without deletion of GABRD and protocols in which the conditioned tone stimuli were cross presented with different nonconditioned stimuli, study showed that when the 2 tone stimuli were largely similar, both genotypes froze similarly to either of them. However, when they differed markedly, the knockout mice froze much more than their wild-type littermates to the nonconditioned but not conditioned stimuli | 28716958 |
| 2018-03-03 11:07:00 | findings suggest that GABAA(delta)R serves as a brake rather than a mediator of GABAergic inhibition in Lateral Amygdala. | 27591789 |
| 2018-01-13 11:36:00 | Reduced GABAA R delta subunit expression and function in dentate gyrus granule cells is sufficient to induce deficits in learning and memory in mice. Findings suggest that the reduction in GABAA R delta subunit-mediated tonic inhibition in dentate gyrus granule cells contributes, at least in part, to deficits in learning and memory associated with chronic stress. | 27163381 |
| Type | IDs |
|---|---|
| Synonymous | AI853201 |
| Gene |
UniProtKB-ID:
GBRD_MOUSE,
Q14AH9_MOUSE
UniprotKB:
P22933,
Q14AH9
UniParc:
UPI00000230A7
EMBL:
BC116836,
BC116832,
S42882,
AH001900
Ensembl:
ENSMUSG00000029054
KO:
mmu:14403
|
| Nucleutide sequences |
EMBL-CDS:
AAB22967.1,
AAA37652.1,
AAI16837.1,
AAI16833.1
Ensembl_TRS:
ENSMUST00000030925
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030925
RefSeq:
XP_006538609.2,
XP_036019573.1,
NP_032098.2,
XP_036019574.1
|
| Others |
UniRef100:
UniRef100_P22933
UniRef90:
UniRef90_P22933
UniRef50:
UniRef50_O14764
UniGene:
Mm.388925
CCDS:
CCDS19028.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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