Delta Subunit-Containing Gamma-Aminobutyric Acid A Receptor Disinhibits Lateral Amygdala and Facilitates Fear Expression in Mice.
Biol. Psychiatry. 2017 Jun 15;81(12):990-1002. Epub 2016 Jul 06
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摘要
BACKGROUND:R to amygdala inhibition and fear. METHODS:(δ)R in regulating inhibition in the lateral amygdala (LA) and fear learning using the combined approaches of immunohistochemistry, electrophysiology, and behavior. RESULTS:(δ)R facilitated long-term potentiation in sensory afferents to LA and permitted the expression of learned fear. CONCLUSIONS:(δ)R may help to prevent excessive suppression of amygdala activity and thus ensure the expression of emotion.
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基因功能
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原始数据
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文献解读
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