TOM1L1 - target of myb1 like 1 membrane trafficking protein-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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10040 TOM1L1

基因描述

Type	Description
Definition	target of myb1 like 1 membrane trafficking protein

研究结论

Date	Results	Publications
2016-07-16 11:04:00	TOM1L1 enhances ERBB2-induced cell invasiveness by promoting invadopodia formation and MT1-MMP trafficking to the plasma membrane.	26899482
2013-06-29 12:08:00	whereas TOM1L1 depletion only slightly affected SRC-induced proliferation of colorectal cancer cells in vitro, it drastically decreased tumor growth in xenografted nude mice.	23023324
2010-11-13 10:31:00	This pattern of Srcasm expression suggests that it may act as a negative regulator in esophageal squamous cell carcinoma cell signaling	20944134
2010-05-10 12:01:00	results imply that TOM1L has a mitogenic effect in Jurkat T-cells and is involved in a novel cell signaling pathway that is crucial for the IL-2 production and expression	20182632
2010-01-21 00:00:00	Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor.	19798056

名称对应

Type	IDs
Synonymous	SRCASM
Gene	UniProtKB-ID: TM1L1_HUMAN, Q8NI65_HUMAN UniprotKB: O75674, Q8NI65 UniParc: UPI0000070028, UPI000003E7E0, UPI0001915414, UPI00000716D1 EMBL: AK223125, AK315039, AK315907, AB065085, CH471109, AJ010071, AC090824, BC029396, KC877665, AC007485 Ensembl: ENSG00000141198 KO: hsa:10040
Nucleutide sequences	EMBL-CDS: EAW94553.1, AAH29396.1, BAH14278.1, CAA08993.1, BAG37522.1, EAW94551.1, BAD96845.1, BAB93522.1 Ensembl_TRS: ENST00000570371, ENST00000536554, ENST00000348161, ENST00000575333, ENST00000575882
Protein sequencees	Ensembl_PRO: ENSP00000460823, ENSP00000343901, ENSP00000458553, ENSP00000443099, ENSP00000458918 RefSeq: NP_001308103.1, NP_001308102.1, NP_001308105.1, NP_005477.2, XP_016879491.1, NP_001308104.1
Others	UniRef100: UniRef100_O75674, UniRef100_Q8NI65 UniRef90: UniRef90_Q8NI65, UniRef90_O75674 UniRef50: UniRef50_Q8NI65, UniRef50_O75674 UniGene: Hs.153504 CCDS: CCDS82160.1, CCDS82161.1, CCDS11582.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
32296183	A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G CotÃ© , Meaghan Daley , Steven Deimling , Alice Desbuleux , AmÃ©lie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , IstvÃ¡n A KovÃ¡cs , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood	2020-04-01	-
30021884	Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck	2018-10-01	-
29987050	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown	2018-07-31	-
28611215	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown	2017-06-27	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
26899482	TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion. Nat Commun ClÃ©ment Chevalier , Guillaume Collin , Simon Descamps , Heiani Touaitahuata , ValÃ©rie Simon , Nicolas Reymond , Laurent Fernandez , Pierre-Emmanuel Milhiet , Virginie Georget , Serge Urbach , Laurence Lasorsa , BÃ©atrice Orsetti , Florence BoissiÃ¨re-Michot , Evelyne Lopez-Crapez , Charles Theillet , Serge Roche , Christine Benistant	2016-01-01	-
23533145	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics Simona Principe , E Ellen Jones , Yunee Kim , Ankit Sinha , Julius O Nyalwidhe , Jasmin Brooks , O John Semmes , Dean A Troyer , Raymond S Lance , Thomas Kislinger , Richard R Drake	2013-05-01	-
23376485	Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. J Proteomics Marco Prunotto , Annarita Farina , Lydie Lane , AgnÃ¨s Pernin , JÃ¼rg Schifferli , Denis F Hochstrasser , Pierre Lescuyer , Solange Moll	2013-04-26	CDH2, GNPDA1, C1orf68, PDCD6IP, PDCD6, TOM1L1, CDH6, IL18BP, DPP3, SNUPN, ARPC5, CDH11, ARPC4, ARPC3, ARPC1B, ACTR3, ACTR2, TSPAN1, ARPC2, ACTR1B, ACTR1A, CDH13, PDIA6, TRAP1, PDZK1IP1, ATP6AP2, DHRS2, NUTF2, FLOT1, PSMD14, RIDA, GLYAT, ZMPSTE24, STUB1, RTN3, LANCL1, CRISP3, SIRPB1, AKR1A1, TFG, TUBA1B, BPNT1, TUBB4B, BTN2A2, NDRG1, RACK1, ST3GAL6, CPQ, WFDC2, BASP1, IFITM3, CDSN, LYPLA1, FAM3C, ACAA2, VAV3, TOMM40, BAIAP2, ATP5H, CEACAM5, CAP1, VAT1, FBLN5, CIB1, GLRX3, PROCR, ARL6IP5, ARPC1A, OLFM4, CEL, CCT7, CCT4, CCT2, NPC2, DNPH1, PAICS, MYL12A, ATP5L, YKT6, PMVK, GNA13, B3GNT2, CCT8, CETP, CFL1, PTGES3, RBBP9, MASP2, CTSC, GIPC1, AHCYL1, IQGAP2, VAMP5, CFTR, ALDH1L1, FTCD, RUVBL2, PGRMC1, FGL2
23023324	Analysis of SRC oncogenic signaling in colorectal cancer by stable isotope labeling with heavy amino acids in mouse xenografts. Mol Cell Proteomics Audrey Sirvent , Oana Vigy , Beatrice Orsetti , Serge Urbach , Serge Roche	2012-12-01	-
22863883	A high-throughput approach for measuring temporal changes in the interactome. Nat. Methods Anders R Kristensen , Joerg Gsponer , Leonard J Foster	2012-09-01	GNPDA1, LOC100128588, PDCD6IP, PDCD6, GNE, TOM1L1, TOM1, RANBP9, SMC4, UBA2, SAE1, FARSB, DNM1L, ABCF2, DPP3, HUWE1, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR3, ACTR2, NUBP2, ARPC2, ACTR1B, ACTR1A, PDIA6, TRAP1, OPTN, NAMPT, RBM12, G3BP1, ABI2, TRIM28, WASF2, TXNDC9, PRMT3, PSME3, DDX39A, PSMD14, PLIN3, HNRNPR, GPHN, POP7, CDK9, STAM2, STUB1, UBE4B, SF3A1, CDKN2A, MAEA, RRAGB, TFG, NPM3, TUBB3, TUBB4A, TUBB4B, NDRG1, MYL9, RACK1, BASP1, YAP1, PRMT5, ARIH2, ACAA2, COG5, PFDN6, EIF3M, SEC23B, SEC23A, CAP2, CAP1, CRTAP, SYNCRIP, VAT1, CARM1, DDX17, HYOU1, IPO7, ATG7, SSSCA1, RNASEH2A, GLRX3, DCTN2, ANP32B, PRDX4, ARPC1A, RPP30, RPP38, ARFGEF2, CCT7, CCT4, CCT2, DRAP1, SMC2, AHSA1, PAIP1, PAICS

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