Polymerase switching in DNA replication.
Mol. Cell. 2007 Aug 17;27(4):523-6
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摘要
Our view of DNA replication has been of two coupled DNA polymerases anchored to the replication fork helicase in a "replisome" complex, synthesizing leading and lagging strands simultaneously. New evidence suggests that three DNA polymerases can be accommodated into the replisome and that polymerases and repair factors are dynamically recruited and engaged without dismantling of the replisome.
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基因功能
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原始数据
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文献解读
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