| Type | Description |
|---|---|
| Definition | beta sliding clamp |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 12:15:00 | In Bacillus subtilis, the interaction stimulates the endonuclease activity of MutL and it is critical for DNA mismatch repair. Conversely, disrupting the interaction between Escherichia coli MutL and the b-clamp only causes a mild mutator phenotype. Here, we determined the structures of the regulatory domains of E. coli and B. subtilis MutL bound to their respective b-clamps | 30916336 |
| 2018-12-29 10:45:00 | Results demonstrate that the beta-clamp of the Escherichia coli replisome strongly inhibits nick translation on the DNA substrate. beta-clamp inhibits the strand displacement activity of Pol I by interfering with the interaction between the finger subdomain of Pol I and the downstream primer-template junction. beta-clamp stimulates the 5' exonuclease property of Pol I to cleave single nucleotides or shorter oligonucleo... | 29924849 |
| 2017-10-07 11:52:00 | structural and mutational analyses of the Hda-beta clamp complex indicate that the interaction of the beta clamp with Hda controls the ability of Hda to interact with DnaA. | 28168278 |
| 2014-09-06 12:22:00 | The Escherichia coli beta clamp can simultaneously bind the replicative polymerase (Pol) III and the conserved Y-family Pol IV, enabling exchange of the two polymerases and rapid bypass of a Pol IV cognate lesion. | 24825884 |
| 2013-07-27 11:10:00 | A structural model of the alphaepsilontheta;:beta2 replicase complex reveals a compact, but still flexible, structure of the complex. | 23580545 |
| Type | IDs |
|---|---|
| Synonymous | ECK3693 |
| Gene |
UniProtKB-ID:
DPO3B_ECOLI
UniprotKB:
P0A988
UniParc:
UPI00001129AC,
UPI0001FB719B
EMBL:
M19876,
J01602,
X04341,
L10328,
M13822,
K02179,
AP009048,
U00096
EnsemblGenome:
b3701,
BAE77593
KO:
ecj:JW3678,
eco:b3701
|
| Nucleutide sequences |
EMBL-CDS:
AAC76724.1,
AAA62052.1,
AAA24510.1,
AAB59150.1,
CAA27869.1,
AAA23695.1,
BAE77593.1,
AAA24512.1
EnsemblGenome_TRS:
AAC76724,
BAE77593
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC76724,
BAE77593
RefSeq:
NP_418156.1
|
| Others |
UniRef100:
UniRef100_P0A990
UniRef90:
UniRef90_P0A990
UniRef50:
UniRef50_P0A990
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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