| Type | Description |
|---|---|
| Definition | DNA polymerase III subunit alpha |
| Date | Results | Publications |
|---|---|---|
| 2017-08-12 10:14:00 | results support a model in which the pol and exo activities of pol III core are effectively independent, and in which recognition of the 3' end of the primer by either alpha or epsilon is governed by the primer stability. | 28263430 |
| 2015-10-31 10:19:00 | Mutation in PHP domain of Pol III alpha ablated interaction with the proofreading subunit. | 25987558 |
| 2015-08-15 11:42:00 | Data show that the tau (tau), alpha (alpha), epsilon (epsilon), and theta (theta;) subunits of III can be assembled in vivo, yielding the trimeric tau3alpha3epsilon3theta;3 complex. | 25918025 |
| 2014-01-04 12:22:00 | The results suggest that competition between UmuD and ssDNA for DNA polymerase III alpha binding is a new mechanism for polymerase exchange. | 23901012 |
| 2013-12-21 11:19:00 | The PHP domain is a major structural element in Pol III and its integrity modulates both the stability and activity of the polymerase. | 23672456 |
| Type | IDs |
|---|---|
| Synonymous | ECK0183, polC, sdgC |
| Gene |
UniProtKB-ID:
DPO3A_ECOLI
UniprotKB:
P10443
UniParc:
UPI00001296D2
EMBL:
AP009048,
D49445,
M19334,
U00096,
U70214,
S52931,
M96394
EnsemblGenome:
BAA77859,
b0184
KO:
eco:b0184,
ecj:JW0179
|
| Nucleutide sequences |
EMBL-CDS:
BAA77859.1,
AAC73295.1,
AAB24889.1,
AAB08613.1,
BAA08424.1,
AAA70369.1,
AAC36920.1
EnsemblGenome_TRS:
BAA77859,
AAC73295
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC73295,
BAA77859
RefSeq:
NP_414726.1
|
| Others |
UniRef100:
UniRef100_P10443
UniRef90:
UniRef90_P10443
UniRef50:
UniRef50_P10443
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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