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9805 SCRN1

9805

SCRN1

secernin 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition secernin 1

研究结论

Date Results Publications
2020-09-26 13:06:00 Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer's disease and not in other tauopathies. 31796108
2017-12-23 12:42:00 Upregulation of SCRN1 is associated with acquired resistance to erlotinib in non-small cell lung cancer. 26883194
2015-10-31 11:16:00 Luciferase report assay showed that the rs6976789 variant T allele influenced the binding ability of miR-148a. Our results suggested that the SCRN1 rs6976789 polymorphism may play an important role in the GC development and progression 25399950
2012-04-26 16:08:00 A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. 22360420
2011-08-20 11:09:00 in synovial sarcoma, metastasis-free survival was significantly higher in the group with high secernin-1 expression compared to low expression; results indicate secernin-1 may be used as a biomarker to predict overall and metastasis-free survival 21385630

名称对应

Type IDs
Synonymous SES1
Gene
UniProtKB-ID: SCRN1_HUMAN, A0A090N7T9_HUMAN, A0A024RA21_HUMAN
UniprotKB: Q12765, A0A090N7T9, A0A024RA21
UniParc: UPI000194EC2F, UPI000019B3D5, UPI0000139435
EMBL: CH471073, BC040492, AK295172, AC004912, AACC02000087, AK289514, D83777, AB071705, AC007285, AK295713
Ensembl: ENSG00000136193
KO: hsa:9805
Nucleutide sequences
EMBL-CDS: BAF82203.1, BAE91926.1, EAW93926.1, BAG58182.1, AAH40492.1, AAQ96874.1, BAA12106.2, EAW93928.1, BAG58557.1, EAL24458.1, EAW93927.1
Gene_ORFName: tcag7.1066, hCG_37324
Ensembl_TRS: ENST00000409497, ENST00000426154, ENST00000425819, ENST00000434476, ENST00000242059
Protein sequencees
Ensembl_PRO: ENSP00000409068, ENSP00000414245, ENSP00000242059, ENSP00000388942, ENSP00000386872
RefSeq: NP_001138985.1, NP_001138986.1, NP_001138987.1, XP_024302775.1, NP_055581.3
Others
UniRef100: UniRef100_Q12765
UniRef90: UniRef90_Q12765
UniRef50: UniRef50_Q12765
UniGene: Hs.520740
CCDS: CCDS47567.1, CCDS47568.1, CCDS5422.1

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