| Type | Description |
|---|---|
| Definition | IST1 factor associated with ESCRT-III |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:23:00 | To learn how certain ESCRT-IIIs shape positively curved membranes, we determined structures of human membrane-bound CHMP1B-only, membrane-bound CHMP1B + IST1, and IST1-only filaments by cryo-EM | 32251413 |
| 2019-11-30 10:39:00 | Visualization of IST1 structures in cells lacking the microtubule-severing enzyme spastin and in cells depleted of specific ESCRT-III components or the ATPase VPS4 demonstrated the contribution of these components to the organization and function of ESCRTs in cells. | 30110633 |
| 2018-02-24 11:22:00 | Nuclear overexpression of OLC1 was associated with clinicopathological parameters and could predict a poor overall survival in gastric adenocarcinoma. | 28038462 |
| 2017-07-01 10:08:00 | The expression of OLC1 in the tumor tissues of lung adenocarcinoma is higher than that in squamous cell carcinoma. | 28532543 |
| 2016-03-12 10:16:00 | Structural and biochemical studies reveal an unusually tight interaction between ULK3 and IST1, an ESCRT-III subunit required for cytokinetic abscission. | 26011858 |
| Type | IDs |
|---|---|
| Synonymous | CHMP8, OLC1 |
| Gene |
UniProtKB-ID:
IST1_HUMAN,
B4DXC9_HUMAN
UniprotKB:
P53990,
B4DXC9
UniParc:
UPI00002335D1,
UPI000204A93F,
UPI000006D3E0,
UPI00017A80C0,
UPI00001393D5,
UPI00001FF5EB,
UPI000006FAD6
EMBL:
D79996,
AK293022,
BC103745,
BC000430,
AK057258,
AC010653,
AK301918,
BC004359,
AK293040,
BC000116,
AC009127,
AB097052
Ensembl:
ENSG00000182149
KO:
hsa:9798
|
| Nucleutide sequences |
EMBL-CDS:
BAG51894.1,
BAF85711.1,
AAI03746.1,
BAA11491.2,
AAH00430.1,
BAF85729.1,
AAH04359.1,
BAC77405.1,
AAH00116.1,
BAG63341.1
Ensembl_TRS:
ENST00000535424,
ENST00000538850,
ENST00000329908,
ENST00000378798,
ENST00000544564,
ENST00000378799,
ENST00000541571,
ENST00000606369
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000475853,
ENSP00000455860,
ENSP00000368076,
ENSP00000438399,
ENSP00000368075,
ENSP00000457844,
ENSP00000463711,
ENSP00000330408
RefSeq:
NP_055576.2,
NP_001257908.1,
NP_001257906.1,
NP_001257905.1,
NP_001257907.1,
NP_001257904.1
|
| Others |
UniRef100:
UniRef100_P53990
UniRef90:
UniRef90_P53990
UniRef50:
UniRef50_P53990
UniGene:
Hs.232194
CCDS:
CCDS59273.1,
CCDS59274.1,
CCDS59272.1,
CCDS59271.1,
CCDS10905.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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