| Type | Description |
|---|---|
| Definition | zinc finger protein 516 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-03 11:56:00 | ZNF516 represses EGFR transcription through the interaction with the CtBP/LSD1/CoREST complex. | 28947780 |
| 2016-04-02 10:48:00 | one interacting gene pair (RBMS3 versus ZNF516) which, even after Bonferroni correction for multiple testing, showed consistently significant effects on hip bone mineral density. | 23045156 |
| 2014-11-08 12:18:00 | ZNF516 promoter methylation was the best biomarker, with both sensitivity and specificity of 90% (AUC = 0.92), results subsequently corroborated in a Prevalence cohort. | 24241165 |
| Type | IDs |
|---|---|
| Synonymous | HsT287 |
| Gene |
UniProtKB-ID:
ZN516_HUMAN,
Q2YDX2_HUMAN
UniprotKB:
Q92618,
Q2YDX2
UniParc:
UPI00005EDD92,
UPI00001394A1
EMBL:
BC108287,
D86975
Ensembl:
ENSG00000101493
KO:
hsa:9658
|
| Nucleutide sequences |
EMBL-CDS:
BAA13211.2,
AAI08288.1
Ensembl_TRS:
ENST00000443185
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000394757
RefSeq:
XP_016881586.1,
XP_011524575.1,
XP_011524571.1,
NP_055458.1,
XP_011524572.1,
XP_011524578.1,
XP_011524577.1,
XP_011524573.1,
XP_011524579.1,
XP_011524576.1
|
| Others |
UniRef100:
UniRef100_Q2YDX2,
UniRef100_Q92618
UniRef90:
UniRef90_Q92618
UniRef50:
UniRef50_Q7TSH3
UniGene:
Hs.436973
CCDS:
CCDS74234.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29507755 |
Cell Discov Yanan Yue , Jun Liu , Xiaolong Cui , Jie Cao , Guanzheng Luo , Zezhou Zhang , Tao Cheng , Minsong Gao , Xiao Shu , Honghui Ma , Fengqin Wang , Xinxia Wang , Bin Shen , Yizhen Wang , Xinhua Feng , Chuan He , Jianzhao Liu |
2018-01-01 | - |
| 28947780 |
ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin. Nat Commun Lifang Li , Xinhua Liu , Lin He , Jianguo Yang , Fei Pei , Wanjin Li , Shumeng Liu , Zhe Chen , Guojia Xie , Bosen Xu , Xia Ting , Zihan Zhang , Tong Jin , Xujun Liu , Wenting Zhang , Shuai Yuan , Ziran Yang , Chongyang Wu , Yu Zhang , Xiaohan Yang , Xia Yi , Jing Liang , Yongfeng Shang , Luyang Sun |
2017-09-25 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 28065597 |
A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. Mol. Cell Zhong Yao , Katelyn Darowski , Nicole St-Denis , Victoria Wong , Fabian Offensperger , Annabel Villedieu , Shahreen Amin , Ramy Malty , Hiroyuki Aoki , Hongbo Guo , Yang Xu , Caterina Iorio , Max Kotlyar , Andrew Emili , Igor Jurisica , Benjamin G Neel , Mohan Babu , Anne-Claude Gingras , Igor Stagljar |
2017-01-19 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25281560 |
J Proteomics Jean-Philippe Lambert , Monika Tucholska , Christopher Go , James D R Knight , Anne-Claude Gingras |
2015-04-06 |
MED6,
GNPDA1,
PDCD6,
MED16,
CHAF1A,
PARP2,
RANBP9,
HUWE1,
RAD50,
KIF20A,
ACTR1A,
PDIA6,
TXNDC9,
PSME3,
MPHOSPH9,
FLOT1,
PLIN3,
DCAF7,
CDK8,
SRRM1,
NPM3,
NDC80,
RBM14,
PIBF1,
HMGN4,
ATP5H,
EIF3M,
CAP2,
NCOA2,
KAT5,
NOP56,
RNASEH2A,
DCTN2,
CENPC,
PAICS,
PDLIM5,
SPAG5,
TAF6L,
RAD51AP1,
IGF2BP3,
RAI1,
SDCCAG3,
SRCAP,
PGRMC1,
RAB10,
BRD8,
SUGT1,
EHMT2,
RNPS1,
AFG3L2,
MSL3,
SEC61B,
TMED2,
ACOT2,
KIF2C,
TOPBP1,
FGFR1OP,
KIF3A,
KAT7,
NUDT5,
SUPT16H,
DCTN3,
SGF29,
MED8,
CDCA5,
ECD,
PHB2,
PDAP1,
EXOSC8,
ZNF257,
PWWP2A,
FLYWCH2,
HAUS1,
TBCB,
DNTTIP1,
CNTROB,
SSX2IP,
LSM12,
C17orf49,
TRAPPC5,
CNP,
CHMP4B,
CP,
CREBBP,
DYNLL2,
CSNK2A2,
CDAN1,
KIF18B,
EME1,
SPC24,
CTBP1,
CTBP2,
ZNF362,
SGO2,
SGO1,
SPICE1,
ZMAT2,
CYLD,
AMOT
|
| 25578880 |
Mol. Cell Jon Dempersmier , Audrey Sambeat , Olga Gulyaeva , Sarah M Paul , Carolyn S S Hudak , Helena F Raposo , Hiu-Yee Kwan , Chulho Kang , Roger H F Wong , Hei Sook Sul |
2015-01-22 |
Ucp1,
Zfp516,
PRDM16
|
| 25378659 |
Genetic loci associated with circulating levels of very long-chain saturated fatty acids. J Lipid Res Rozenn N Lemaitre , Irena B King , Edmond K Kabagambe , Jason H Y Wu , Barbara McKnight , Ani Manichaikul , Weihua Guan , Qi Sun , Daniel I Chasman , Millennia Foy , Lu Wang , Jingwen Zhu , David S Siscovick , Michael Y Tsai , Donna K Arnett , Bruce M Psaty , Luc Djousse , Yii-Der I Chen , Weihong Tang , Lu-Chen Weng , Hongyu Wu , Majken K Jensen , Audrey Y Chu , David R Jacobs , Stephen S Rich , Dariush Mozaffarian , Lyn Steffen , Eric B Rimm , Frank B Hu , Paul M Ridker , Myriam Fornage , Yechiel Friedlander |
2015-01-01 | - |
| 24241165 |
Epigenetics Priscilla Brebi , Leonel Maldonado , Maartje G Noordhuis , Carmen Ili , Pamela Leal , Patricia Garcia , Mariana Brait , Judit Ribas , Christina Michailidi , Jimena Perez , Ethan Soudry , Oscar Tapia , Pablo Guzman , Sergio Muñoz , Leander Van Neste , Wim Van Criekinge , Rafael Irizarry , David Sidransky , Juan C Roa , Rafael Guerrero-Preston |
2014-02-01 |
FKBP6,
ZNF516
|
| 23602568 |
The protein interaction landscape of the human CMGC kinase group. Cell Rep Markku Varjosalo , Salla Keskitalo , Audrey Van Drogen , Helka Nurkkala , Anton Vichalkovski , Ruedi Aebersold , Matthias Gstaiger |
2013-04-25 |
MED6,
PDCD6IP,
FRAT1,
TROAP,
MED16,
RWDD2B,
HUWE1,
EDIL3,
ARPC1B,
HIPK3,
FRY,
AKAP9,
SUGP2,
RASA4,
CDK2,
RBM7,
CDK3,
CDK4,
PSME3,
CDK5,
FLOT1,
DDX39A,
CDK6,
CDK7,
HNRNPR,
DCAF7,
CDK8,
SRRM1,
CDK9,
SF3B4,
CDKN1A,
AKAP8,
CDKN1B,
STUB1,
CDKN1C,
CDKN2A,
PAK4,
CDKN2B,
ZNF267,
CDKN2C,
CDKN2D,
NPM2,
CACNG2,
RBM14,
HAX1,
BAIAP2,
PFDN6,
EIF3M,
SEC23B,
ENOX2,
MYBBP1A,
CHERP,
NOP56,
UBD,
MAB21L2,
DRAP1,
PRPF8,
CDC42EP3,
USP39,
PTGES3,
YME1L1,
NUP50,
HBS1L,
AHCYL1,
ZMYND11,
ZNF460,
CPSF4,
TRAFD1,
MAGED2,
RNPS1,
SUB1,
SRSF8,
AFG3L2,
MSL3,
STIP1,
EBNA1BP2,
SNRNP27,
STON1,
NUDT21,
CPSF6,
CHD2,
SNRNP35,
DIDO1,
WDR5,
KRR1,
FOXN3,
CLASRP,
KPTN,
WDR6,
SUPT16H,
CHEK2,
AKAP11,
EGLN2,
MED8,
GLCCI1,
GABARAP,
U2AF2,
CHUK,
EVI5L
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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{{author.size}} |
目前还没有研究热点人员