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9610 RIN1

9610

RIN1

Ras and Rab interactor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition Ras and Rab interactor 1

研究结论

Date Results Publications
2021-03-13 13:21:00 Role of RIN1 on telomerase activity driven by EGF-Ras mediated signaling in breast cancer. 33069695
2017-09-30 13:38:00 Findings suggest that RIN1 plays an important oncogenic role in clear cell renal cell carcinoma malignancy by activation of EGFR signaling through interacting with Rab25. 28612496
2017-08-19 11:58:00 Smad2 is a key scaffold, allowing RIN1 to act as a GTP exchange factor for MFN2-GTPase activation to promote mitochondrial ATP synthesis and suppress superoxide production during mitochondrial fusion. 27184078
2017-05-13 16:58:00 Overexpression experiments in tandem with pull-down assays indicated that specific Ser291/292 phosphorylation of RIN1 favored binding to activated Ras 27137893
2017-02-18 12:15:00 analysis of a novel deregulated mechanism in chronic myeloid leukemia patients, indicating BIN1 and RIN1 as players in the maintenance of the abnormal RTK signaling in this hematological disease 26194865

名称对应

Type IDs
Gene
UniProtKB-ID: RIN1_HUMAN, A0A0S2Z4U0_HUMAN
UniprotKB: Q13671, A0A0S2Z4U0
UniParc: UPI0000E4457F, UPI000013F14D
EMBL: CH471076, KU178481, L36463, BC014417
Ensembl: ENSG00000174791
KO: hsa:9610
Nucleutide sequences
EMBL-CDS: AAB67270.1, AAH14417.1, ALQ33939.1, EAW74512.1
Gene_ORFName: hCG_20306
Ensembl_TRS: ENST00000311320
Protein sequencees
Ensembl_PRO: ENSP00000310406
RefSeq: NP_001350489.1, NP_004283.2, NP_001350488.1, XP_016874076.1
Others
UniRef100: UniRef100_Q13671
UniRef90: UniRef90_Q13671
UniRef50: UniRef50_Q13671
UniGene: Hs.1030
CCDS: CCDS31614.1

全选

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研究热度

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