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947978 ftsY

947978

ftsY

signal recognition particle receptor

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition signal recognition particle receptor

研究结论

Date Results Publications
2020-08-01 11:48:00 A nucleotide sensing function of the P-loop assists FtsY in nucleotide-binding.The binding of magnesium in the nucleotide site causes the reorientation of the beta- and gamma- phosphate groups toward the jaws of the P-loop and stabilizes the binding of the nucleotide, creating a network of hydrogen and water-bridge interactions in FtsY structure. 31520694
2016-04-23 11:32:00 FtsY can target the membrane co-translationally. 25653387
2015-06-27 11:20:00 analysis of the ribosome-SRP-FtsY cotranslational targeting complex in the closed state 25775537
2013-07-06 10:02:00 The cryo-electron microscopy structure of this 'false' early complex with EspP revealed an ordered M domain of SRP protein Ffh making two ribosomal contacts, and the NG domains of Ffh and FtsY forming a distorted, flexible heterodimer. 23563142
2011-07-16 10:10:00 Data show that FtsY, the bacterial SRalpha homologue, binds to the exposed C4/C5 loops of SecY, the central component of the bacterial Sec translocon, and that the same loops serve also as binding sites for SecA and the ribosome. 21255212

名称对应

Type IDs
Synonymous ECK3448
Gene
UniProtKB-ID: FTSY_ECOLI
UniprotKB: P10121
UniParc: UPI000012AD05
EMBL: U00096, AP009048, X04398, U00039
EnsemblGenome: BAE77829, b3464
KO: eco:b3464, ecj:JW3429
Nucleutide sequences
EMBL-CDS: CAA27984.1, AAB18439.1, AAC76489.1, BAE77829.1
EnsemblGenome_TRS: AAC76489, BAE77829
Protein sequencees
EnsemblGenome_PRO: AAC76489, BAE77829
RefSeq: NP_417921.1
Others
UniRef100: UniRef100_P10121
UniRef90: UniRef90_P10121
UniRef50: UniRef50_P10121

全选

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