| Type | Description |
|---|---|
| Definition | scaffold protein for iron-sulfur cluster assembly |
| Date | Results | Publications |
|---|---|---|
| 2016-04-30 11:18:00 | We have demonstrated that a single mutation in the scaffold protein IscU rendered E. coli viability strictly dependent upon a functional CyaY. | 25996492 |
| 2015-10-03 11:11:00 | Data indicate that the single point mutation IscU_D39A affects the 2Fe-2S coordination geometry. | 25447544 |
| 2013-06-01 10:02:00 | Data indicate that IscU exists as two interconverting species: one (S) is largely structured with all four peptidyl-prolyl bonds trans; the other (D) contains an ordered domain that stabilizes two cis peptidyl-prolyl peptide bonds. | 23333622 |
| 2012-09-08 11:00:00 | The iron-sulfur cluster assembly in E. coli IscU is an IscS mediated biosynthetic process. | 22348472 |
| 2010-09-06 11:41:00 | study determined the crystal structures of IscS-IscU and IscS-TusA complexes providing the first insight into their different modes of binding and the mechanism of sulfur transfer | 20404999 |
| Type | IDs |
|---|---|
| Synonymous | ECK2526, nifU, yfhN |
| Gene |
UniProtKB-ID:
ISCU_ECOLI
UniprotKB:
P0ACD4
UniParc:
UPI0000130120
EMBL:
AP009048,
U00096
EnsemblGenome:
b2529,
BAA16423
KO:
eco:b2529,
ecj:JW2513
|
| Nucleutide sequences |
EMBL-CDS:
BAA16423.1,
AAC75582.1
EnsemblGenome_TRS:
AAC75582,
BAA16423
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA16423,
AAC75582
RefSeq:
NP_417024.1
|
| Others |
UniRef100:
UniRef100_P0ACD6
UniRef90:
UniRef90_P0ACD6
UniRef50:
UniRef50_P0ACD6
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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