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946869 zipA

946869

zipA

cell division protein ZipA

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition cell division protein ZipA

研究结论

Date Results Publications
2020-06-20 12:03:00 ZipA attachment enables FtsZ-GMPCPP (where GMPCPP is a GTP analogue with a reduced level of hydrolysis) to assemble in several distinct ways: (i) two-dimensional polymerization at the membrane and (ii) three-dimensional polymerization from the membrane into the solution phase where this may be associated with the formation of higher-order complexes. 31390865
2019-10-26 12:24:00 Here, the authors use in vivo cross-linking to show that FtsA and ZipA indeed interact directly. They identify the exposed surface of FtsA helix 7, which also participates in binding to ATP through its internal surface, as a key interface needed for the interaction with ZipA. 30478085
2019-09-14 11:58:00 When lower, more physiological levels of the soluble, cytoplasmic domain of Escherichia coli membrane proteins ZipA (sZipA) are attached to lipids, cytoskeletal proteins FtsZ assemble into highly dynamic vortices similar to those assembled with FtsA or other membrane anchors. ZipA does not dampen FtsZ dynamics but acts as a passive membrane attachment for FtsZ filaments as they treadmill. 29921670
2017-12-30 12:33:00 study demonstrates a link between amino acid metabolism and ZipA, another essential cell division protein that binds directly to FtsZ and tethers it to the cytoplasmic membrane 29061666
2016-08-13 11:14:00 YciB protein directly interacted with ZipA. Furthermore, the septum localization of ZipA, an essential protein of cell division, is disturbed in a DeltayciB mutant 26391555

名称对应

Type IDs
Synonymous ECK2407
Gene
UniProtKB-ID: ZIPA_ECOLI
UniprotKB: P77173
UniParc: UPI000016812D
EMBL: U74650, U00096, AP009048
EnsemblGenome: BAA16284, b2412
KO: ecj:JW2404, eco:b2412
Nucleutide sequences
EMBL-CDS: AAB42061.1, BAA16284.1, AAC75465.1
EnsemblGenome_TRS: AAC75465, BAA16284
Protein sequencees
EnsemblGenome_PRO: AAC75465, BAA16284
RefSeq: NP_416907.1
Others
UniRef100: UniRef100_C4ZVU3
UniRef90: UniRef90_Q8FFC0
UniRef50: UniRef50_Q8FFC0

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