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946529 sbcB

946529

sbcB

exodeoxyribonuclease I

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition exodeoxyribonuclease I

研究结论

Date Results Publications
2018-07-21 10:33:00 Data show that replication forks form a palindrome-like structural intermediate that requires nucleolytic processing by SbcC-SbcD and exonuclease I (ExoI) before chromosome replication can be completed. 29208713
2017-12-30 10:58:00 ExoI is primarily responsible for more efficiently abort template-switches on the lagging strand and that its ability to be recruited by single-strand DNA binding protein plays a critical role in quasipalindrome-associated mutagenesis avoidance and strand bias. 28605670
2013-08-10 10:36:00 Possible mechanisms for ExoI processive digestion are proposed based upon crystal structures of ExoI in complex with four different single-stranded DNA substrates. 23609540
2010-05-31 11:12:00 Study hypothesized that RecJ and XonA blunt the double-strand end (created by the replication fork reversal)in order to produce SOS(Con) expression. 20304994
2010-01-21 00:00:00 Data show structure of ExoI in complex with thymidine 5'-monophosphate, indicating that conserved active site contains a unique metal-binding position when compared with orthologous sites in the Klenow fragment, T4 DNA polymerase and dnaQ. 18219121

名称对应

Type IDs
Synonymous ECK2005, cpeA, exoI, rmuA, xonA
Gene
UniProtKB-ID: EX1_ECOLI, A0A0G3HGF9_ECOLI
UniprotKB: P04995, A0A0G3HGF9
UniParc: UPI000012A2BA
EMBL: AP009048, U00096, U00009, AM235175, J02641
EnsemblGenome: BAA15839, b2011
KO: eco:b2011, ecj:JW1993
Nucleutide sequences
EMBL-CDS: BAA15839.1, AAC75072.1, AAA16417.1, AAA19938.1, CAJ84171.1
EnsemblGenome_TRS: BAA15839, AAC75072
Protein sequencees
EnsemblGenome_PRO: BAA15839, AAC75072
RefSeq: NP_416515.1
Others
UniRef100: UniRef100_P04995
UniRef90: UniRef90_P04995
UniRef50: UniRef50_P04995

全选

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