| Type | Description |
|---|---|
| Definition | DNA mismatch endonuclease of the very short patch (VSP) mismatch repair pathway |
| Date | Results | Publications |
|---|---|---|
| 2015-04-04 11:32:00 | Authors propose that lesions formed upon aminoglycoside treatment are preferentially repaired by Vsr without SOS induction in Escherichia coli and by mismatch repair when very short patch mismatch repair is impaired. | 24946128 |
| 2010-09-27 11:09:00 | unusual patterns of base pair stability in the Dcm target sequence can explain how the Vsr endonuclease specifically recognizes the mismatched Dcm target sequence and intercalates into the DNA | 20541519 |
| 2010-01-21 00:00:00 | Results suggest a mobile MutS-MutL complex in DNA mismatch repair signalling, that leaves the DNA mismatch prior to, or at the time of, activation of downstream effector molecules such as Vsr. | 19474347 |
| 2010-01-21 00:00:00 | Vsr carries out a hydrolytic reaction with inversion of stereochemistry at phosphorus, compatible with an in-line attack of water and a pentacovalent transition state with trigonal bipyramidal geometry | 16188275 |
| 2010-01-21 00:00:00 | MutL recruits the Vsr and MutH to sites of DNA damage. | 19376855 |
| Type | IDs |
|---|---|
| Synonymous | ECK1958 |
| Gene |
UniProtKB-ID:
VSR_ECOLI
UniprotKB:
P09184
UniParc:
UPI00001680EF
EMBL:
X13330,
M32307,
U00096,
AP009048
EnsemblGenome:
BAA15787,
b1960
KO:
eco:b1960,
ecj:JW1943
|
| Nucleutide sequences |
EMBL-CDS:
CAA31707.1,
BAA15787.1,
AAC75026.1,
AAA03724.1
EnsemblGenome_TRS:
AAC75026,
BAA15787
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC75026,
BAA15787
RefSeq:
NP_416469.1
|
| Others |
UniRef100:
UniRef100_P09184
UniRef90:
UniRef90_P09184
UniRef50:
UniRef50_P09184
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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