| Type | Description |
|---|---|
| Definition | bifunctional folylpolyglutamate synthetase/dihydrofolate synthetase |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 10:40:00 | The uridylyltransferase GlnD and tRNA modification GTPase MnmE allosterically control Escherichia coli folylpoly-gamma-glutamate synthase FolC. | 30089654 |
| 2010-01-21 00:00:00 | mutagenesis study to identify structural elements of folylpolyglutamate synthetase that are directly responsible for the functional differences between the E. coli and the Lactobacillus casei enzymes | 18232714 |
| 2010-01-21 00:00:00 | analysis of an unexpected dihydrofolate binding site in Escherichia coli FolC | 15705579 |
| 2007-11-05 21:38:00 | N-terminus verified by Edman degradation on complete protein | 3040739 |
| Type | IDs |
|---|---|
| Synonymous | ECK2309, dedC |
| Gene |
UniProtKB-ID:
FOLC_ECOLI
UniprotKB:
P08192
UniParc:
UPI000012AB4B
EMBL:
J02808,
U00096,
M32445,
AP009048,
M68934
EnsemblGenome:
BAA16164,
b2315
KO:
eco:b2315,
ecj:JW2312
|
| Nucleutide sequences |
EMBL-CDS:
AAA23966.1,
BAA16164.1,
AAC75375.1,
AAA23808.1,
AAA23802.1
EnsemblGenome_TRS:
AAC75375,
BAA16164
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA16164,
AAC75375
RefSeq:
NP_416818.1
|
| Others |
UniRef100:
UniRef100_P08192
UniRef90:
UniRef90_P08192
UniRef50:
UniRef50_P08192
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30089654 |
J Biol Chem Irina A Rodionova , Norman Goodacre , Jimmy Do , Ali Hosseinnia , Mohan Babu , Peter Uetz , Milton H Saier |
2018-10-05 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 19783991 |
Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting. Nat. Chem. Biol. Ranjana Pathania , Soumaya Zlitni , Courtney Barker , Rahul Das , David A Gerritsma , Julie Lebert , Emilia Awuah , Giuseppe Melacini , Fred A Capretta , Eric D Brown |
2009-11-01 |
ftsA,
folA,
acpP,
erpA,
dxr,
folC,
lpp,
ydiL,
ddlB,
fabB,
ispB,
tolC,
murA,
yidC,
tsaE,
rpsR,
lolA
|
| 18724364 |
A domino effect in antifolate drug action in Escherichia coli. Nat. Chem. Biol. Yun Kyung Kwon , Wenyun Lu , Eugene Melamud , Nurussaba Khanam , Andrew Bognar , Joshua D Rabinowitz |
2008-10-01 |
folC
|
| 18232714 |
Biochemistry Yi Sheng , Nurussaba Khanam , Yonit Tsaksis , Xiao-ming Shi , Qing-shi Lu , Andrew L Bognar |
2008-02-26 |
folC
|
| 16738554 |
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. Tomoya Baba , Takeshi Ara , Miki Hasegawa , Yuki Takai , Yoshiko Okumura , Miki Baba , Kirill A Datsenko , Masaru Tomita , Barry L Wanner , Hirotada Mori |
2006-01-01 |
yafF,
ileS,
dapB,
ispH,
ftsA,
ftsZ,
folA,
murE,
ftsI,
lspA,
ftsL,
acpP,
murF,
mraY,
lpxC,
murD,
secA,
ftsQ,
secM,
can,
lpxB,
lpxA,
erpA,
dapD,
tsf,
bamA,
rseP,
ispU,
cdsA,
dnaE,
lpxD,
fabZ,
tilS,
accA,
yafN,
yagG,
pyrH,
lptD,
hemB,
dxr,
eno,
ispF,
dxs,
ispA,
adk,
ftsK,
dnaX,
rplT,
rpmA,
entD,
folD,
mrdB,
mrdA,
nadD,
fldA,
glnS,
lptG,
cydA,
pheT,
metK,
folC,
murJ,
infA,
cydC,
serS,
lpxK,
msbA,
rpsA,
kdsB,
mukF,
mukB,
mukE,
asnS,
fabA,
rplY,
ribD,
yceQ,
rne,
fabG,
holB,
tmk,
lolE,
lolD,
lolC,
purB,
cohE,
minE,
minD,
ribA,
pth,
fabD,
prs,
ispE,
lolB,
hemA,
prmC,
kdsA,
pgsA,
mqsA
|
| 16397293 |
Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner |
2006-01-01 |
pmrR,
yfaS,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeF,
yoeB,
yohO,
arnE,
ypdJ,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
yifN,
wecF,
yigE,
blr,
yggP,
cpxP,
ygaY,
hdfR,
thiS,
yedN,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
glvC,
yhaM,
tdcG,
ytfR,
yehH,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
gapC,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
yedS,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yaiX,
yoeA,
yneM
|
| 16738553 |
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi |
2006-01-01 |
pmrR,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeB,
yohO,
arnE,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
wecF,
yigE,
blr,
yggP,
cpxP,
hdfR,
thiS,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
yhaM,
tdcG,
ytfR,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yneM,
ykfM,
ylcI,
yciY,
yncL,
ylcH,
ynhF,
yciZ,
ydgU,
ypfM,
ymgI,
ymgJ,
dinQ
|
| 15705579 |
J Biol Chem Magali Mathieu , Guy Debousker , Sophie Vincent , Fabrice Viviani , Nathalie Bamas-Jacques , Vincent Mikol |
2005-05-13 | - |
| 15690043 |
Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature Gareth Butland , José Manuel PeregrÃn-Alvarez , Joyce Li , Wehong Yang , Xiaochun Yang , Veronica Canadien , Andrei Starostine , Dawn Richards , Bryan Beattie , Nevan Krogan , Michael Davey , John Parkinson , Jack Greenblatt , Andrew Emili |
2005-02-03 |
yjjV,
dnaK,
ileS,
idnD,
carB,
murE,
aceF,
murD,
gcd,
can,
yadG,
aceE,
lpxB,
lpd,
tsf,
sufD,
ldcC,
accA,
metN,
panC,
ispF,
yajQ,
ybaY,
adk,
htpG,
ftsK,
dnaX,
fau,
loiP,
napD,
yedE,
ybdL,
hscC,
ybeD,
glf,
rlmH,
ubiF,
pgm,
sucB,
rsuA,
pheT,
ybhK,
moaC,
moaD,
moaE,
ybhF,
folC,
moeB,
moeA,
ybjQ,
serC,
kdsB,
ycbX,
uup,
cspG,
ymdF,
ndk,
ycfH,
nagK,
cobB,
purB,
bluR,
dhaK,
sufB,
ispE,
narH,
narG,
narJ,
yciU,
ychJ,
adhE,
topA,
rnb,
fabI,
tyrR,
hybO,
ynbC,
ynbD,
ycjY,
ydcP,
narZ,
ydcZ,
mcbR,
gadB,
hipA,
ydfR,
ynfB,
intQ,
topB,
rnt,
intA,
gloA,
nemR,
grxD,
ydhR,
ydiB,
ppsR,
ydaY,
thrS
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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