| Type | Description |
|---|---|
| Definition | DNA replication terminus site-binding protein |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 11:24:00 | We demonstrate that the replisome remains stably bound after encountering a Tus-ter complex from the non-permissive direction. Furthermore, the replisome is only transiently blocked, and continues replication beyond the barrier. Additionally, we demonstrate that these barriers affect sister chromosome segregation by visualizing specific chromosomal loci in the presence and absence of the Tus protein. | 27166373 |
| 2015-10-31 11:04:00 | The study presents a model for replication fork arrest by the Escherichia coli Tus-Ter complex. | 26007657 |
| 2010-01-21 00:00:00 | Data suggest that increased negative supercoiling enhances DnaB unwinding activity, thereby reducing the duration of the Tus-DnaB interaction and leading to decreased Tus activity. | 16238625 |
| 2010-01-21 00:00:00 | As the replication fork helicase unwinds one side of the DNA sequence Ter, a conserved cytosine flips out of the duplex and binds to Tus, thereby creating a locked complex that blocks the advancing helicase. | 16950091 |
| 2007-11-05 21:38:00 | N-terminus verified by Edman degradation on mature peptide | 2687269 |
| Type | IDs |
|---|---|
| Synonymous | ECK1605, tau |
| Gene |
UniProtKB-ID:
TUS_ECOLI
UniprotKB:
P16525
UniParc:
UPI000011127F
EMBL:
AP009048,
D90037,
U41101,
U00096,
X04065
EnsemblGenome:
b1610,
BAA15348
KO:
ecj:JW1602,
eco:b1610
|
| Nucleutide sequences |
EMBL-CDS:
AAA82083.1,
BAA15348.1,
AAC74682.1,
CAA27699.1,
BAA14085.1
EnsemblGenome_TRS:
AAC74682,
BAA15348
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA15348,
AAC74682
RefSeq:
NP_416127.1
|
| Others |
UniRef100:
UniRef100_C4ZY73
UniRef90:
UniRef90_Q8FHA8
UniRef50:
UniRef50_Q9L6X9
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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