nhaA - Na(+):H(+) antiporter NhaA-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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944758 nhaA

基因描述

Type	Description
Definition	Na(+):H(+) antiporter NhaA

研究结论

Date	Results	Publications
2021-02-06 13:51:00	An angular motion of a conserved four-helix bundle facilitates alternating access transport in the TtNapA and EcNhaA transporters.	33257549
2020-12-05 13:01:00	Alternative proton-binding site and long-distance coupling in Escherichia coli sodium-proton antiporter NhaA.	32973095
2019-04-13 11:24:00	findings indicate that alternative mechanisms sustain EcNhaA activity in the absence of canonical ion-binding residues and that the conserved lysines confer structural stability.	30409911
2018-09-29 10:18:00	analysis of NhaA pH-dependent activation by molecular dynamics simulation of atomic details of proton-coupled transport across membrane	27708266
2017-07-15 10:45:00	Lysine 300 has an essential role in stability but not electrogenic transport of Escherichia coli NhaA	28330875

名称对应

Type	IDs
Synonymous	ECK0020, ant, antA, hyc
Gene	UniProtKB-ID: NHAA_ECOLI UniprotKB: P13738 UniParc: UPI0000000D18 EMBL: AP009048, U00096, S67239, J03879 EnsemblGenome: BAB96592, b0019 KO: eco:b0019, ecj:JW0018
Nucleutide sequences	EMBL-CDS: AAB20348.1, AAC73130.1, BAB96592.1, AAA23448.2 EnsemblGenome_TRS: BAB96592, AAC73130
Protein sequencees	EnsemblGenome_PRO: AAC73130, BAB96592 RefSeq: NP_414560.1
Others	UniRef100: UniRef100_P13738 UniRef90: UniRef90_P13738 UniRef50: UniRef50_P13738

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
33257549	An angular motion of a conserved four-helix bundle facilitates alternating access transport in the TtNapA and EcNhaA transporters. Proc Natl Acad Sci U S A Gal Masrati , Ramakanta Mondal , Abraham Rimon , Amit Kessel , Etana Padan , Erik Lindahl , Nir Ben-Tal	2020-12-15	-
32973095	Alternative proton-binding site and long-distance coupling in Escherichia coli sodium-proton antiporter NhaA. Proc Natl Acad Sci U S A Jack A Henderson , Yandong Huang , Oliver Beckstein , Jana Shen	2020-10-13	-
30409911	Replacement of Lys-300 with a glutamine in the NhaA Na⁺/H⁺ antiporter of Escherichia coli yields a functional electrogenic transporter. J Biol Chem Miyer PatiÃ±o-Ruiz , Manish Dwivedi , Octavian CÄlinescu , Mehmet Karabel , Etana Padan , Klaus Fendler	2019-01-04	-
28330875	Lysine 300 is essential for stability but not for electrogenic transport of the Escherichia coli NhaA Na⁺/H⁺ antiporter. J Biol Chem Octavian CÄlinescu , Manish Dwivedi , Miyer PatiÃ±o-Ruiz , Etana Padan , Klaus Fendler	2017-05-12	-
28077870	The role of interfacial lipids in stabilizing membrane protein oligomers. Nature Kallol Gupta , Joseph A C Donlan , Jonathan T S Hopper , Povilas Uzdavinys , Michael Landreh , Weston B Struwe , David Drew , Andrew J Baldwin , Phillip J Stansfeld , Carol V Robinson	2017-01-19	-
27708266	Mechanism of pH-dependent activation of the sodium-proton antiporter NhaA. Nat Commun Yandong Huang , Wei Chen , David L Dotson , Oliver Beckstein , Jana Shen	2016-10-06	-
27021484	The Ec-NhaA antiporter switches from antagonistic to synergistic antiport upon a single point mutation. Sci Rep Manish Dwivedi , Shahar Sukenik , Assaf Friedler , Etana Padan	2016-01-01	-
26417087	NhaA antiporter functions using 10 helices, and an additional 2 contribute to assembly/stability. Proc. Natl. Acad. Sci. U.S.A. Etana Padan , Tsafi Danieli , Yael Keren , Dudu Alkoby , Gal Masrati , Turkan Haliloglu , Nir Ben-Tal , Abraham Rimon	2015-10-13	nhaA
26392528	Simulating the function of sodium/proton antiporters. Proc. Natl. Acad. Sci. U.S.A. Raphael Alhadeff , Arieh Warshel	2015-10-06	nhaA
25422503	Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights. J. Gen. Physiol. Chiara Lee , Shoko Yashiro , David L Dotson , Povilas Uzdavinys , So Iwata , Mark S P Sansom , Christoph von Ballmoos , Oliver Beckstein , David Drew , Alexander D Cameron	2014-12-01	-

研究热度

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