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944750 dnaK

944750

dnaK

chaperone protein DnaK

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition chaperone protein DnaK

研究结论

Date Results Publications
2021-01-02 12:50:00 J-Domain Proteins in Bacteria and Their Viruses. 32305462
2019-10-12 10:39:00 The authors find that large aggregates or bulky, native-like substrates activate the DnaK-ClpB complex, whereas a smaller, permanently unfolded protein or extended, short peptides fail to stimulate it. 29643454
2019-05-25 10:56:00 We identified that molecular chaperone-encoding dnaK, cell division protein-encoding cpoB and repeat protein-encoding rhsC were associated with the cost reduction for pMCR1_1943, which may represent new mechanisms for host bacterial strains to compensate fitness costs imposed by large plasmids and warrant further studies. 30586457
2019-04-20 11:17:00 Plasmid carrying an E. coli chromosomal fragment harboring chaperone protein DnaK capable of encoding truncated N-terminal ATPase domain (244 aa) can suppress Lon Protease mutant phenotypes in copy number dependent manner. Systematic deletion analysis of dnaK reveals that 169 aa peptide is enough for the suppression of Methyl Methanesulfonate sensitivity phenotype of Deltalon mutant. 30614541
2018-12-22 10:28:00 While preventing the formation of lethal IpaC aggregates, DnaK promoted the incorporation of IpaC into large and dynamic complexes (LDCs) restricted at the bacterial pole through nucleoid occlusion. Direct and reversible IpaC-DnaK interactions as part of large dynamic complexes (LDCs) drive polarization through nucleoid occlusion. Polar accumulation was associated with DnaKJ-dependent substrate folding. 29795186

名称对应

Type IDs
Synonymous ECK0014, groPAB, groPC, groPF, grpC, grpF, seg
Gene
UniProtKB-ID: DNAK_ECOLI
UniprotKB: P0A6Y8
UniParc: UPI000004C26F
EMBL: AP009048, U00096, D10765, K01298, M12565
EnsemblGenome: BAB96589, b0014
KO: eco:b0014, ecj:JW0013
Nucleutide sequences
EMBL-CDS: BAB96589.1, AAA23694.1, AAA23692.1, BAA01595.1, AAC73125.1
EnsemblGenome_TRS: BAB96589, AAC73125
Protein sequencees
EnsemblGenome_PRO: BAB96589, AAC73125
RefSeq: NP_414555.1
Others
UniRef100: UniRef100_A7ZHA4
UniRef90: UniRef90_A7MIK5
UniRef50: UniRef50_P71331

全选

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