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9440 MED17

9440

MED17

mediator complex subunit 17

protein-coding

Homo sapiens

基因描述

Type Description
Definition mediator complex subunit 17

研究结论

Date Results Publications
2015-10-03 11:19:00 These findings suggest that hMED17 may play essential roles in switching between transcription and nucleotide excision repair. 25482373
2015-04-25 12:51:00 TRAP80 is a selective regulator of hepatic lipogenesis and is required for LXR-dependent SREBP-1c activation. 25437875
2012-06-23 10:47:00 Studies indicate that the activation domain of p53 (p53AD) binds directly to the MED17 subunit of Mediator, whereas the p53 C-terminal domain (p53CTD) binds the MED1 subunit. 21326907
2011-01-29 10:58:00 the p. L371P mutation in MED17 is a founder mutation in the Caucasus Jewish community and that homozygosity for this mutation is associated with infantile cerebral and cerebellar atrophy with poor myelination. 20950787

名称对应

Type IDs
Synonymous CRSP6, CRSP77, DRIP80, SRB4, TRAP80
Gene
UniProtKB-ID: MED17_HUMAN
UniprotKB: Q9NVC6
UniParc: UPI00001FA1CE, UPI000013CD1D
EMBL: AF104254, AC022150, AF105421, AK001674, AK023209, AF117657, BC021101, AK022156
Ensembl: ENSG00000042429
KO: hsa:9440
Nucleutide sequences
EMBL-CDS: AAH21101.1, AAD30856.1, BAA91827.1, BAG51169.1, AAD12723.1, BAB13973.1, AAD22031.2
Ensembl_TRS: ENST00000251871
Protein sequencees
Ensembl_PRO: ENSP00000251871
RefSeq: NP_004259.3
Others
UniRef100: UniRef100_Q9NVC6
UniRef90: UniRef90_Q9NVC6
UniRef50: UniRef50_Q9NVC6
UniGene: Hs.444931
CCDS: CCDS8295.1

全选

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