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9390 SLC22A13

9390

SLC22A13

solute carrier family 22 member 13

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 22 member 13

研究结论

Date Results Publications
2020-04-25 12:08:00 A dysfunctional missense variant of OAT10 decreases both gout risk and serum uric acid levels, suggesting OAT10 to be physiologically involved in urate reabsorption in the human kidney. 31780526
2015-06-06 11:44:00 An adenovirus expressing ORCTL3 leads to growth inhibition of renal tumours in vivo and to substantial destruction of patients' kidney tumour cells ex vivo 24769897
2014-11-22 11:58:00 Since ORCTL3 targets fatty acid metabolism in transformed cells and induces an ER stress specifically in these cells, it reveals a novel therapeutic interference option for tumor cells. 25001539
2014-03-01 10:02:00 Expression of SLC22A13 stimulates efflux of aspartate and glutamate at the basolateral membrane in renal collecting duct. 24147638
2010-06-30 22:06:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614

名称对应

Type IDs
Synonymous OAT10, OCTL1, OCTL3, ORCTL-3, ORCTL3
Gene
UniProtKB-ID: S22AD_HUMAN
UniprotKB: Q9Y226
UniParc: UPI0000171691, UPI00006E2254
EMBL: BC035973, AB010438, AB026898, CH471055, AK315301
Ensembl: ENSG00000172940
KO: hsa:9390
Nucleutide sequences
EMBL-CDS: BAA76350.1, AAH35973.1, BAG37706.1, BAA77625.1, EAW64527.1
Ensembl_TRS: ENST00000311856
Protein sequencees
Ensembl_PRO: ENSP00000310241
RefSeq: NP_004247.2
Others
UniRef100: UniRef100_Q9Y226
UniRef90: UniRef90_Q9Y226
UniRef50: UniRef50_Q9Y226
UniGene: Hs.225941
CCDS: CCDS2676.1

全选

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研究热度

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