| Type | Description |
|---|---|
| Definition | single-pass membrane protein with aspartate rich tail 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 11:00:00 | the human MCU-EMRE complex, which constitutes the minimal channel components among metazoans, provides a framework for future mechanistic studies on MCU. | 31080062 |
| 2019-12-28 12:15:00 | SMDT1 overexpression induced mitochondrial mediated apoptosis. | 30782485 |
| 2017-10-14 12:12:00 | Here, the authors determine the transmembrane orientation of EMRE, and show that its known MCU-activating function is mediated by the interaction of transmembrane helices from both proteins. | 27099988 |
| 2016-09-10 10:44:00 | Our experiments provide novel details about how MCU/EMRE is regulated by MICU1 and an original approach to investigate MCU/EMRE activation in intact cells. | 26489515 |
| 2013-12-28 12:16:00 | EMRE is essential for in vivo uniporter current and additionally bridges the calcium-sensing role of MICU1 and MICU2 with the calcium-conducting role of MCU. | 24231807 |
| Type | IDs |
|---|---|
| Synonymous | C22orf32, DDDD, EMRE |
| Gene |
UniProtKB-ID:
EMRE_HUMAN
UniprotKB:
Q9H4I9
UniParc:
UPI000006EA19
EMBL:
AL449243,
CR456453,
CH471095,
Z82192,
AL021878,
AK312142,
BC024237
Ensembl:
ENSG00000272835,
ENSG00000274112,
ENSG00000272901,
ENSG00000183172
KO:
hsa:91689
|
| Nucleutide sequences |
EMBL-CDS:
CAC15000.1,
AAH24237.1,
EAW60488.1,
BAG35078.1,
CAG30339.1
Ensembl_TRS:
ENST00000331479,
ENST00000615504,
ENST00000607293,
ENST00000571525
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000485029,
ENSP00000475471,
ENSP00000459368,
ENSP00000327467
RefSeq:
NP_201575.3,
XP_011528811.1
|
| Others |
UniRef100:
UniRef100_Q9H4I9
UniRef90:
UniRef90_Q9H4I9
UniRef50:
UniRef50_Q9H4I9
UniGene:
Hs.306083
CCDS:
CCDS14031.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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