| Type | Description |
|---|---|
| Definition | aryl hydrocarbon receptor interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 12:11:00 | AIP protected BCL6 from ubiquitin-mediated proteasomal degradation by FBXO11 by binding to UCHL1. | 31042473 |
| 2020-05-09 10:17:00 | The entire coding sequence of the AIP gene, along with exon/intron boundaries and the untranslated regions of 41 newly recruited pituitary adenoma patients, were sequenced for germline variations.The AIP c.911G>A: p.Arg304Gln (rs104894190) variant was detected in only two patients with functional PA: one with somatotropinoma and one with prolactinoma. None of the corticotrophinomas had AIP gene alterations. | 30461320 |
| 2020-02-15 10:18:00 | results suggest that a crosstalk between the tumor and its microenvironment plays a key role in the invasive nature of AIP-mutation-positive tumors | 30867568 |
| 2019-12-07 10:46:00 | AIP interacts with the pathway on multiple levels, including a physical interaction with both the main regulatory PRKAR1A and catalytic PRKACA subunits.AIP protein levels are regulated both by translation and the ubiquitin/proteasome pathway. | 29726992 |
| 2019-09-21 11:56:00 | We propose a user-friendly risk categorisation system that can reliably group patients into high-risk, moderate-risk and low-risk groups for the presence of AIP mutations, thus providing guidance in identifying patients at high risk of carrying an AIP mutation. This risk score is based on a cohort with high prevalence of AIP mutations and should be applied cautiously in other populations. | 29440248 |
| Type | IDs |
|---|---|
| Synonymous | ARA9, FKBP16, FKBP37, PITA1, SMTPHN, XAP-2, XAP2 |
| Gene |
UniProtKB-ID:
AIP_HUMAN,
G9I2H4_HUMAN
UniprotKB:
O00170,
G9I2H4
UniParc:
UPI000013DBC1,
UPI000016B170
EMBL:
EF066504,
BC104797,
U31913,
AM236341,
EF066510,
JN561683,
EF066502,
BC104827,
EF066505,
U78521
Ensembl:
ENSG00000110711
KO:
hsa:9049
|
| Nucleutide sequences |
EMBL-CDS:
AAB59004.1,
AAI04798.1,
ABK60081.1,
ABK60083.1,
CAJ85657.1,
AAI04828.1,
ABK60084.1,
ABK60082.1,
AAB39923.1,
AEW31446.1
Ensembl_TRS:
ENST00000279146
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000279146
RefSeq:
XP_024304529.1,
NP_003968.3,
NP_001289888.1,
NP_001289889.1
|
| Others |
UniRef100:
UniRef100_G9I2H4,
UniRef100_O00170
UniRef90:
UniRef90_O00170
UniRef50:
UniRef50_O00170
UniGene:
Hs.412433
CCDS:
CCDS8168.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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