| Type | Description |
|---|---|
| Definition | ubiquitin conjugating enzyme E2 M |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:22:00 | Ubiquitin conjugating enzyme E2 M promotes apoptosis in osteoarthritis chondrocytes via Wnt/beta-catenin signaling. | 32819607 |
| 2021-01-23 13:00:00 | UBE2M promotes cell proliferation via the beta-catenin/cyclin D1 signaling in hepatocellular carcinoma. | 32012120 |
| 2020-08-12 16:14:00 | All reported DCN1 inhibitors are able to induce remarkable accumulation of cullin 3 and its substrate NRF2, indicating therapeutic potential of DCN1 inhibitors for human diseases that may benefit from upregulation of cullin 3 and NRF2 | 31668094 |
| 2020-04-04 12:48:00 | The present study was designed to assess the effects of Nedd8conjugating enzyme UBE2M knockdown on intrahepatic cholangiocarcinoma cells, and to determine the potential underlying mechanisms. UBE2M and associated protein expression levels were determined via immunohistochemistry and western blotting | 31545502 |
| 2020-02-29 11:10:00 | REVIEW: Targeting DCN1-UBC12 Protein-Protein Interaction for Regulation of Neddylation Pathway | 31898237 |
| Type | IDs |
|---|---|
| Synonymous | UBC-RS2, UBC12, hUbc12 |
| Gene |
UniProtKB-ID:
UBC12_HUMAN,
A0A024R4T4_HUMAN
UniprotKB:
P61081,
A0A024R4T4
UniParc:
UPI0000020ECC
EMBL:
CH471135,
BC058924,
GQ891447,
AF075599,
AB012191,
BT006754
Ensembl:
ENSG00000130725
KO:
hsa:9040
|
| Nucleutide sequences |
EMBL-CDS:
BAA33145.1,
AAP35400.1,
AAC26141.1,
AAH58924.1,
EAW72612.1,
EAW72613.1,
ADO22309.1
Gene_ORFName:
hCG_2045958
Ensembl_TRS:
ENST00000253023
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000253023
RefSeq:
NP_003960.1
|
| Others |
UniRef100:
UniRef100_P61081
UniRef90:
UniRef90_P61081
UniRef50:
UniRef50_P61081
UniGene:
Hs.406068
CCDS:
CCDS12987.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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