例如:"NBL1", "4681", "drought"
收藏
8999 CDKL2

8999

CDKL2

cyclin dependent kinase like 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition cyclin dependent kinase like 2

研究结论

Date Results Publications
2021-02-27 13:52:00 Decreased CDKL2 expression is correlated with the progression and poor prognosis of glioma. 32173142
2019-08-17 12:15:00 In HeLa cells infected with HSV-2, we detected significantly reduced expression of CDKN2A and CDKL2 and demonstrated the negative regulation effect of miRNA-H4-5p on these two target genes. 30953292
2018-11-10 11:33:00 Results showed that the methylation levels of CDKL2 were higher in hepatocellular carcinoma (HCC) cell lines and tissues but the mRNA expression levels decreased both in HCC tissues and cell lines. CDKL2 status seems to correlate with tumor size and may play an important role in hepatocarcinogenesis. 30292871
2015-09-05 11:09:00 High CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression. 25333262
2010-01-21 00:00:00 We hypothesized that LA might induce dissociation of p56(Lck) from CD4, thus leading to its downmodulation. 16631599

名称对应

Type IDs
Synonymous KKIAMRE, P56
Gene
UniProtKB-ID: CDKL2_HUMAN, B4DH08_HUMAN, A0A140VJG1_HUMAN, J3KNE8_HUMAN
UniprotKB: Q92772, B4DH08, A0A140VJG1, J3KNE8
UniParc: UPI000048026C, UPI00017A6F74, UPI000006D070
EMBL: AC108939, HM005348, AK312490, AK294866, AC096759, KF495695, BC093981, BC093646, U35146, CH471057, AC104828
Ensembl: ENSG00000138769
KO: hsa:8999
Nucleutide sequences
EMBL-CDS: BAG35392.1, EAX05740.1, AAC50918.1, AAH93981.1, AAH93646.1, BAG57969.1, AEE60948.1
Ensembl_TRS: ENST00000429927, ENST00000307465
Protein sequencees
Ensembl_PRO: ENSP00000412365, ENSP00000306340
RefSeq: XP_016864300.1, XP_016864298.1, NP_001317653.1, XP_006714469.1, NP_003939.1, XP_016864299.1
Others
UniRef100: UniRef100_B4DH08, UniRef100_J3KNE8, UniRef100_Q92772
UniRef90: UniRef90_Q92772
UniRef50: UniRef50_Q92772
UniGene: Hs.591698
CCDS: CCDS3570.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员